Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.37 |
| ▸ | KCNQ4 | P56696 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12168471 | 0.88 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL12098094 | 0.87 | ALDH1A1 (0.32) | ALDH1A1MAPTRECQL | |
| SCHEMBL15567283 | 0.83 | NPC1 (0.38) | ALDH1A1MAPTCYP1A2HPGDKDM4E | |
| SCHEMBL9727365 | 0.82 | POLB (0.44) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10233688 | 0.80 | VRK1 (0.30) | ALDH1A1 | |
| SCHEMBL18286865 | 0.79 | HTT (0.30) | — | |
| SCHEMBL900315 | 0.78 | — | — | |
| SCHEMBL901186 | 0.76 | HTT (0.32) | — | |
| SCHEMBL900540 | 0.76 | — | — | |
| SCHEMBL900513 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748348-B2 | 3-(3,4-dihydro-2H-benzo [1,4]oxazin-6-yl)-1H-pyrimidin-2,4-dione compounds as herbicides | BASF SE (DE) | 2014-06-10 | — | — | US | disclosed |
| US-8481723-B2 | 3-(3,4-dihydro-2H-benzo [1,4]oxazin-6-yl)-1H-Pyrimidin-2,4-dione compounds as herbicides | BASF SE (DE) | 2013-07-09 | — | — | US | disclosed |
| WO-2011057935-A1 | 3-(3,4-DIHYDRO-2H-BENZO [1,4]OXAZIN-6-YL)-1H-PYRIMIDIN-2,4-DIONE COMPOUNDS AS HERBICIDES | BASF SE (DE) | 2011-05-19 | — | — | WO | disclosed |