Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19810812 | 0.86 | MAOA (0.41) | CA12CA1CA2CA9 | |
| SCHEMBL19820997 | 0.76 | — | — | |
| SCHEMBL20644295 | 0.71 | SIGMAR1 (0.35) | STK17B | |
| SCHEMBL19821012 | 0.70 | — | — | |
| SCHEMBL19820976 | 0.68 | HRH3 (0.32) | CA12CA9 | |
| SCHEMBL18020472 | 0.67 | SIGMAR1 (0.48) | — | |
| SCHEMBL14808600 | 0.67 | MAOB (0.65) | STK17B | |
| Iodide SCHEMBL30281983 | 0.66 | MAOB (0.63) | STK17B | |
| SCHEMBL19820999 | 0.65 | — | — | |
| SCHEMBL19821094 | 0.64 | ABCC4 (0.40) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016127924-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-08-18 | — | — | WO | disclosed |