Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 9/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.37 |
| ▸ | FPGS | Q05932 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17500359 | 0.87 | DHFR (0.72) | DHFRLMNAMTHFD1NOS1NOS3 | |
| SCHEMBL17500357 | 0.87 | DHFR (0.72) | DHFRLMNAMTHFD1NOS1NOS3 | |
| SCHEMBL3408027 | 0.87 | DHFR (0.72) | DHFRLMNAMTHFD1NOS1NOS3 | |
| SCHEMBL18020461 | 0.87 | MTHFD1 (0.53) | DHFRLMNAMTHFD1NOS1NOS3 | |
| SCHEMBL24179695 | 0.80 | DHFR (0.74) | DHFRLMNAMTHFD1SOSTFPGS | |
| SCHEMBL20910478 | 0.80 | DHFR (0.74) | DHFRLMNAMTHFD1SOSTFPGS | |
| SCHEMBL18402509 | 0.80 | DHFR (0.83) | DHFRLMNAMTHFD1SOSTFPGS | |
| SCHEMBL13509375 | 0.79 | DHFR (0.89) | DHFRLMNAMTHFD1SOSTFPGS | |
| Folinic Acid SCHEMBL21498299 | 0.78 | DHFR (1.00) | DHFRLMNAMTHFD1SOSTFPGS | |
| Leucovorin SCHEMBL3031362 | 0.78 | DHFR (1.00) | DHFRLMNAMTHFD1SOSTFPGS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9415113-B2 | Targeting monomers and polymers having targeting blocks | UNIVERSITY OF WASHINGTON (US) | 2016-08-16 | — | — | US | disclosed |