⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468408 | 0.82 | — | — | |
| SCHEMBL471600 | 0.82 | — | — | |
| SCHEMBL468407 | 0.82 | — | — | |
| SCHEMBL8837918 | 0.75 | GAA (0.36) | — | |
| SCHEMBL8837919 | 0.75 | GAA (0.36) | — | |
| SCHEMBL8837916 | 0.75 | GAA (0.36) | — | |
| SCHEMBL11234585 | 0.75 | ABAT (0.41) | — | |
| SCHEMBL31337363 | 0.73 | CHRNB2 (0.39) | — | |
| SCHEMBL9084173 | 0.73 | — | — | |
| SCHEMBL27997686 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260132258-A1 | COMPOUND, COMPOSITION, SURFACE TREATMENT AGENT, METHOD FOR MANUFACTURING ARTICLE, AND ARTICLE | AGC Inc. (JP) | 2026-05-14 | — | — | US | disclosed |
| US-20250064823-A1 | THIADIAZINE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2025-02-27 | — | — | US | disclosed |
| WO-2025013911-A1 | COMPOUND, COMPOSITION, SURFACE TREATMENT AGENT, METHOD FOR PRODUCING ARTICLE, AND ARTICLE | ＡＧＣ株式会社 | 2025-01-16 | — | — | WO | disclosed |
| US-12194050-B2 | Thiadiazine derivatives | RICHTER GEDEON NYRT. (HU) | 2025-01-14 | — | — | US | disclosed |
| EP-3820865-A1 | THIADIAZINE DERIVATIVES | Richter Gedeon Nyrt. (HU) | 2021-05-19 | — | — | EP | disclosed |
| CN-112424198-A | Thiadiazine derivatives | 吉瑞工厂 | 2021-02-26 | — | — | CN | disclosed |
| US-10544141-B2 | Derivatives and methods of treating hepatitis B infections | NOVIRA THERAPEUTICS, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| US-10544141-B2 | Derivatives and methods of treating hepatitis B infections | NOVIRA THERAPEUTICS, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| WO-2020012423-A1 | THIADIAZINE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2020-01-16 | — | — | WO | disclosed |
| US-20190077800-A1 | DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | NOVIRA THERAPEUTICS, INC. | 2019-03-14 | — | — | US | disclosed |
| US-4906755-A | Esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3-(4H)-one and related compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-03-06 | — | — | US | disclosed |
| CN-1037901-A | Hexahydro--8-hydroxyl-2, the ester related compounds of 6-methylene radical-2H-quinolizine-3 (4H)-ketone and phase thereof | MERRELL DOW PHARMA (US) | 1989-12-13 | — | — | CN | disclosed |
| EP-0330824-A1 | Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of cardiac arrhythmias | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-09-06 | — | — | EP | disclosed |
| EP-0329932-A2 | Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments | MERRELL PHARMACEUTICALS INC. (US) | 1989-08-30 | — | — | EP | disclosed |
| CN-87107629-A | Esters of hexahydro-8-hydroxy-2, 6-methylene-2H-quinolizin-3 (4H) -one and related compounds | — | 1988-06-15 | — | — | CN | disclosed |
| EP-0266730-A1 | Esters of hexadydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one and related compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-05-11 | — | — | EP | disclosed |
| EP-0155721-B1 | NOVEL ANTI-ARRHYTHMIC AMINO-ALCOHOLS | AKZO N.V. (NL) | 1987-09-23 | — | — | EP | disclosed |
| US-4613619-A | Anti-arrhythmic amino-alcohols | AKZO N.V. (NL) | 1986-09-23 | — | — | US | disclosed |
| EP-0155721-A1 | Novel anti-arrhythmic amino-alcohols | AKZO N.V. (NL) | 1985-09-25 | — | — | EP | disclosed |
| US-4142051-A | Arylaminoimidazoline derivatives | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1979-02-27 | — | — | US | disclosed |