SCHEMBL468408

SCHEMBL468408

O=C(Cl)C1CC=CCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL468407 1.00
SCHEMBL471600 1.00
SCHEMBL11536956 0.87 MEN1 (0.36)
SCHEMBL180205 0.82
SCHEMBL10379597 0.80 ALDH1A1 (0.47)
SCHEMBL11353841 0.79 CES2 (0.33)
SCHEMBL468425 0.78
SCHEMBL16922155 0.78
SCHEMBL468428 0.78
SCHEMBL91180 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113754666-A Benzopyrazine compound and synthesis method thereof 凯美克(上海)医药科技有限公司 2021-12-07 CN claimed
US-20250250249-A1 NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS NATIONAL YANG MING CHIAO TUNG UNIVERSITY (TW) 2025-08-07 US disclosed
US-12312326-B2 Substituted benzimidazole derivatives as D-amino acid oxidase (DAAO) inhibitors Tseng, Yufeng Jane (US) 2025-05-27 US disclosed
US-20250059317-A1 POLYMERIC CYCLOALIPHATIC EPOXIDES ARKEMA FRANCE (FR) 2025-02-20 US disclosed
CN-119361222-A Self-repairing termite-proof cable 广州岭南电缆股份有限公司 2025-01-24 CN disclosed
EP-4457220-A1 POLYMERIC CYCLOALIPHATIC EPOXIDES ARKEMA FRANCE (FR) 2024-11-06 EP disclosed
US-12129242-B2 Substituted benzimidazole derivatives as D-amino acid oxidase (DAAO) inhibitors Tseng, Yufeng Jane (US) 2024-10-29 US disclosed
EP-3512840-B1 NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS TSENG YUFENG JANE (US) 2024-03-06 EP disclosed
EP-4289425-A2 NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS Tseng, Yufeng, Jane (US) 2023-12-13 EP disclosed
CN-114369063-B Pyrazolyl acrylonitrile compound and preparation method and application thereof 沈阳农业大学 2023-09-26 CN disclosed
US-4142051-A Arylaminoimidazoline derivatives CHEMIE LINZ AKTIENGESELLSCHAFT (AT) 1979-02-27 US disclosed
US-4141991-A Ferrocene derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1979-02-27 US disclosed
US-4018930-A ANALGESICS, SEDATIVES, TRANQUILIZERS ENDO LABORATORIES, INC. (US) 1977-04-19 US disclosed
US-4001218-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-01-04 US disclosed
US-3998827-A HYPOTENSIVE AGENTS THE UPJOHN COMPANY (US) 1976-12-21 US disclosed
US-3991199-A ANALGESICS AND SEDATIVES ENDO LABORATORIES, INC. (US) 1976-11-09 US disclosed
US-3984455-A Prostaglandin E1 analogs THE UPJOHN COMPANY (US) 1976-10-05 US disclosed
US-3982011-A ANTIBIOTICS, ANIMAL GROWTH PROMOTERS BAYER AKTIENGESELLSCHAFT (DT) 1976-09-21 US disclosed
US-3959300-A Novel indolobenzazepine derivatives, useful as tranquilizers ENDO LABORATORIES, INC. (US) 1976-05-25 US disclosed
US-3931153-A BACTERICIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed