SCHEMBL18020876

SCHEMBL18020876

CC1(C)c2ccccc2-c2ccc(-c3cc(-c4ccc5c6ccccc6c6ccccc6c5c4)cc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)c3)cc21

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PTGER4 P35408 1/20 0.33
PGR P06401 1/20 0.33
PDK2 Q15119 3/20 0.32
TSPO P30536 1/20 0.32
HDAC4 P56524 1/20 0.32
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12865725 0.96 KDM4E (0.44) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL18020754 0.96 KDM4E (0.44) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL18020872 0.95 PDK2 (0.37) KDM4EATML3MBTL1PGRPDK2
SCHEMBL18020739 0.95 KDM4E (0.41) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL18020883 0.95 KDM4E (0.41) KDM4EATML3MBTL1PGRPDK2
SCHEMBL18020885 0.95 KDM4E (0.35) KDM4EATML3MBTL1PGRPDK2
SCHEMBL17878941 0.94 KDM4E (0.40) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL19061227 0.94 L3MBTL1 (0.42) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL18020680 0.94 KDM4E (0.42) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL12306594 0.94 L3MBTL1 (0.46) KDM4EATML3MBTL1PTGER4PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11245081-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-02-08 US disclosed
US-20200227657-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORP (US) 2020-07-16 US disclosed
US-10644247-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-05-05 US disclosed
US-20160240792-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-18 US disclosed
US-20160240792-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200227657-A1 Organic Electroluminescent Materials and Devices CBX2, DDX3X, CBX7 KDM4E 1842/4885ATM 4460/4885L3MBTL1 803/4885
US-10644247-B2 Organic electroluminescent materials and devices CBX2, DDX3X, CBX7 KDM4E 1842/4885ATM 4460/4885L3MBTL1 803/4885
US-20160240792-A1 Organic Electroluminescent Materials and Devices CBX2, DDX3X, CBX7 KDM4E 1842/4885ATM 4460/4885L3MBTL1 803/4885
US-11245081-B2 Organic electroluminescent materials and devices CBX2, DDX3X, CBX7 KDM4E 1842/4885ATM 4460/4885L3MBTL1 803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.