SCHEMBL18020877

SCHEMBL18020877

c1ccc(-c2ccc(-c3cc(-c4ccc5sc6ccc(-c7ccccc7)cc6c5c4)cc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)c3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.50
▸ ATM Q13315 2/20 0.50
▸ KDM4E B2RXH2 1/20 0.50
▸ TSPO P30536 2/20 0.39
▸ KMT2A Q03164 4/20 0.37
▸ IL1R1 P14778 1/20 0.37
▸ LIMK1 P53667 1/20 0.36
▸ HDAC4 P56524 1/20 0.36
▸ MEN1 O00255 3/20 0.36
▸ ALDH1A1 P00352 3/20 0.36
▸ MAPT P10636 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ PIM3 Q86V86 1/20 0.36
▸ HSD17B10 Q99714 2/20 0.36
▸ PTGER4 P35408 1/20 0.35
▸ DNM1 Q05193 1/20 0.34
▸ ROCK1 Q13464 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ BRCA1 P38398 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18020865 0.99 ATM (0.49) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL22590247 0.97 ATM (0.50) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL17166667 0.97 ATM (0.50) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL17166836 0.97 ATM (0.50) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL20706866 0.97 L3MBTL1 (0.53) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL10041363 0.96 L3MBTL1 (0.51) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL18020874 0.96 L3MBTL1 (0.42) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL22672366 0.95 L3MBTL1 (0.45) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL24810819 0.95 L3MBTL1 (0.44) L3MBTL1ATMKDM4ETSPOKMT2A
SCHEMBL16904449 0.95 L3MBTL1 (0.44) L3MBTL1ATMKDM4ETSPOKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11245081-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-02-08 — — US disclosed
US-20200227657-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORP (US) 2020-07-16 — — US disclosed
US-10644247-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-05-05 — — US disclosed
US-20160240792-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-18 — — US disclosed
US-20160240792-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200227657-A1 Organic Electroluminescent Materials and Devices CBX2, DDX3X, CBX7 L3MBTL1 803/4885ATM 4460/4885KDM4E 1842/4885
US-10644247-B2 Organic electroluminescent materials and devices CBX2, DDX3X, CBX7 L3MBTL1 803/4885ATM 4460/4885KDM4E 1842/4885
US-20160240792-A1 Organic Electroluminescent Materials and Devices CBX2, DDX3X, CBX7 L3MBTL1 803/4885ATM 4460/4885KDM4E 1842/4885
US-11245081-B2 Organic electroluminescent materials and devices CBX2, DDX3X, CBX7 L3MBTL1 803/4885ATM 4460/4885KDM4E 1842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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