SCHEMBL18020880

SCHEMBL18020880

c1ccc(-c2cccc(-c3cc(-c4ccc5c6ccccc6c6ccccc6c5c4)cc(-c4ccc5c6cc(-c7ccccc7)ccc6n(-c6ccccc6)c5c4)c3)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.49
▸ ATM Q13315 2/20 0.49
▸ KDM4E B2RXH2 1/20 0.49
▸ TSPO P30536 2/20 0.38
▸ AVPR1A P37288 1/20 0.36
▸ KMT2A Q03164 3/20 0.35
▸ IL1R1 P14778 1/20 0.35
▸ HDAC4 P56524 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ HTT P42858 2/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ MAPT P10636 2/20 0.35
▸ NR4A2 P43354 1/20 0.35
▸ RXRA P19793 1/20 0.35
▸ RXRB P28702 1/20 0.35
▸ HSP90AA1 P07900 2/20 0.34
▸ FAAH O00519 1/20 0.34
▸ PKM P14618 1/20 0.34
▸ MGLL Q99685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18020882 0.98 L3MBTL1 (0.50) L3MBTL1ATMKDM4ETSPOAVPR1A
SCHEMBL20363010 0.96 L3MBTL1 (0.51) L3MBTL1ATMKDM4ETSPOAVPR1A
SCHEMBL17562341 0.96 L3MBTL1 (0.51) L3MBTL1ATMKDM4ETSPOAVPR1A
SCHEMBL18020741 0.95 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOAVPR1A
SCHEMBL23370635 0.95 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOAVPR1A
SCHEMBL23370616 0.95 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOAVPR1A
SCHEMBL18020722 0.95 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOAVPR1A
SCHEMBL18020875 0.95 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOAVPR1A
SCHEMBL23370504 0.95 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOAVPR1A
SCHEMBL18020881 0.95 L3MBTL1 (0.55) L3MBTL1ATMKDM4ETSPOAVPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11245081-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-02-08 — — US disclosed
US-20200227657-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORP (US) 2020-07-16 — — US disclosed
US-10644247-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-05-05 — — US disclosed
US-20160240792-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-18 — — US disclosed
US-20160240792-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200227657-A1 Organic Electroluminescent Materials and Devices CBX2, DDX3X, CBX7 L3MBTL1 803/4885ATM 4460/4885KDM4E 1842/4885
US-10644247-B2 Organic electroluminescent materials and devices CBX2, DDX3X, CBX7 L3MBTL1 803/4885ATM 4460/4885KDM4E 1842/4885
US-20160240792-A1 Organic Electroluminescent Materials and Devices CBX2, DDX3X, CBX7 L3MBTL1 803/4885ATM 4460/4885KDM4E 1842/4885
US-11245081-B2 Organic electroluminescent materials and devices CBX2, DDX3X, CBX7 L3MBTL1 803/4885ATM 4460/4885KDM4E 1842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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