SCHEMBL1802180

SCHEMBL1802180

O=[C]c1ccc(CCl)cc1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CYP2A6 P11509 1/20 0.31
LOXL2 Q9Y4K0 1/20 0.31
FFAR1 O14842 2/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10766574 0.80 FFAR1 (0.34) FFAR1
SCHEMBL3012910 0.77 FFAR1 (0.38) FFAR1TSHR
SCHEMBL104811 0.76 APP (0.32)
SCHEMBL97582 0.76 CA1 (0.52) CA1CA2CYP3A4TSHR
SCHEMBL3266647 0.75 FFAR1 (0.37) CA2FFAR1TSHR
SCHEMBL23091413 0.74 IDO1 (0.46) CYP2A6LOXL2FFAR1CYP3A4TSHR
SCHEMBL4921070 0.74 HRH3 (0.32) CYP2A6LOXL2FFAR1CYP3A4TSHR
SCHEMBL200142 0.74 LOXL2 (0.58) CA2CYP2A6LOXL2TSHR
SCHEMBL6249906 0.74 TSHR (0.43) CYP2A6LOXL2FFAR1CYP3A4TSHR
SCHEMBL1516489 0.74 TSHR (0.43) CA1CA2FFAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3692083-B1 NOVEL POLYMERS, METHODS FOR PREPARING SAME, AND USES THEREOF PARTICULARLY FOR METAL CAPTURE UNIV PARIS SACLAY (FR) 2024-05-29 EP claimed
EP-3692083-A1 NOVEL POLYMERS, METHODS FOR PREPARING SAME, AND USES THEREOF PARTICULARLY FOR METAL CAPTURE Université Paris-Saclay (FR) 2020-08-12 EP claimed
EP-3692081-A1 NOVEL GRAFT POLYMERS, METHODS FOR PREPARING SAME, AND USES THEREOF PARTICULARLY FOR METAL CAPTURE Université Paris-Saclay (FR) 2020-08-12 EP claimed
CN-109053527-B Synthetic method and application of high-molecular cationic bleaching activator 江南大学 2020-05-08 CN claimed
EP-3133069-B1 BCR-ABL DIPLOID INHIBITOR, PREPARATION METHOD THEREFOR, AND USES THEREOF SHENZHEN YONGZE PHARMACEUTICAL CO LTD (CN) 2019-09-18 EP claimed
EP-3078374-B1 INDOMETHACIN ANALOGS FOR THE TREATMENT OF CASTRATE-RESISTANT PROSTATE CANCER UNIV VANDERBILT (US) 2019-06-19 EP claimed
WO-2019068961-A1 NOVEL POLYMERS, METHODS FOR PREPARING SAME, AND USES THEREOF PARTICULARLY FOR METAL CAPTURE UNIVERSITE PARIS-SUD (FR) 2019-04-11 WO claimed
WO-2019068962-A1 NOVEL GRAFT POLYMERS, METHODS FOR PREPARING SAME, AND USES THEREOF PARTICULARLY FOR METAL CAPTURE UNIVERSITE PARIS-SUD (FR) 2019-04-11 WO claimed
CN-109053527-A A kind of synthetic method and application of macromolecule cation type bleach-activating 江南大学 2018-12-21 CN claimed
CN-104877807-B A kind of synthetic method of polymerizable cationic type bleach-activating 江南大学 2018-04-13 CN claimed
CN-102863383-A Preparation method of oxygen bleaching activator tribasic copper chloride (TBCC) UNIV EAST CHINA SCIENCE & TECH 2013-01-09 CN claimed
EP-1833815-B1 A PROCESS FOR PREPARATION OF IMATINIB BASE INST FARMACEUTYCZNY (PL) 2010-09-15 EP claimed
EP-1143970-B1 PYRIDINE COMPOUNDS, USE AND PREPARATION THEREOF SOUTHERN RES INST (US) 2010-07-21 EP claimed
US-6949678-B2 Oxime ester photoinitiators CIBA SPECIALTY CHEMICALS CORP. (US) 2005-09-27 US claimed
US-20010012596-A1 For resist applications; thermostability, storage stability CIBA SPECIALTY CHEMICALS CORP. 2001-08-09 US claimed
EP-0594540-B1 Antiretroviral acyl compounds CIBA GEIGY AG (CH) 1998-04-01 EP claimed
CN-1093701-A Antiretroviral hydrazine derivative CIBA GEIGY AG (CH) 1994-10-19 CN claimed
EP-0594540-A1 Antiretroviral acyl compounds CIBA-GEIGY AG (CH) 1994-04-27 EP claimed
US-4868241-A POLYVINYL ALCOHOL MODIFIED WITH BENZOIC ACID DERIVATIVE AMERICAN CYANAMID COMPANY (US) 1989-09-19 US claimed
EP-0231922-A2 Electron beam and X-ray resists AMERICAN CYANAMID COMPANY (US) 1987-08-12 EP claimed