Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394176 | 0.77 | NPSR1 (0.44) | NPSR1TSHRKDM4CKDM4ESMN1; SMN2 | |
| SCHEMBL8951086 | 0.70 | NPSR1 (1.00) | NPSR1TSHRKDM4CKDM4ESMN1; SMN2 | |
| SCHEMBL1009945 | 0.68 | KDM4C (0.52) | NPSR1TSHRKDM4CKDM4ESMN1; SMN2 | |
| SCHEMBL5433655 | 0.68 | NPSR1 (0.46) | NPSR1TSHRKDM4CKDM4ESMN1; SMN2 | |
| SCHEMBL29977899 | 0.67 | NPSR1 (0.56) | NPSR1KDM4CKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL16418573 | 0.67 | NPSR1 (0.56) | NPSR1KDM4CKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL11089588 | 0.67 | KDM4C (0.50) | NPSR1TSHRKDM4CKDM4ESMN1; SMN2 | |
| SCHEMBL13279753 | 0.67 | ALDH1A1 (0.41) | NPSR1TSHRKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL4714263 | 0.65 | KDM4C (0.49) | NPSR1TSHRKDM4CKDM4ESMN1; SMN2 | |
| SCHEMBL6617911 | 0.65 | NPSR1 (0.48) | NPSR1KDM4ESMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016128298-A1 | SUBSTITUTED 2-THIOIMIDAZOLYL-CARBOXAMIDES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-08-18 | — | — | WO | disclosed |