Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 4/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18022468 | 1.00 | KEAP1 (0.55) | KEAP1NFE2L2ALDH1A1TSHRLMNA | |
| SCHEMBL4121227 | 0.93 | ALDH1A1 (0.67) | KEAP1NFE2L2ALDH1A1TSHRLMNA | |
| SCHEMBL19327371 | 0.93 | ALDH1A1 (0.67) | KEAP1NFE2L2ALDH1A1TSHRLMNA | |
| SCHEMBL4122426 | 0.92 | TSHR (0.66) | KEAP1NFE2L2ALDH1A1TSHRLMNA | |
| SCHEMBL5154230 | 0.90 | TSHR (0.65) | KEAP1NFE2L2ALDH1A1TSHRLMNA | |
| SCHEMBL18468145 | 0.89 | KDM4E (0.58) | KEAP1NFE2L2ALDH1A1TSHRLMNA | |
| SCHEMBL8657075 | 0.88 | KEAP1 (0.55) | KEAP1NFE2L2ALDH1A1LMNATP53 | |
| SCHEMBL28122618 | 0.86 | TSHR (0.66) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL19895380 | 0.84 | POLB (0.56) | KEAP1NFE2L2ALDH1A1TSHRLMNA | |
| SCHEMBL13800968 | 0.83 | MAPT (0.68) | KEAP1NFE2L2ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9563138-B2 | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2017-02-07 | — | — | US | disclosed |
| US-9563138-B2 | Electrophotographic photoreceptor, process cartridge, and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2017-02-07 | — | — | US | disclosed |
| US-20160238955-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJIFILM BUSINESS INNOVATION CORP. (JP) | 2016-08-18 | — | — | US | disclosed |
| US-20160238955-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJIFILM BUSINESS INNOVATION CORP. (JP) | 2016-08-18 | — | — | US | disclosed |