Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28310888 | 0.81 | TLR8 (0.68) | ALDH1A1GAATLR8KDM4EHRH4 | |
| SCHEMBL18023063 | 0.81 | ALDH1A1 (0.62) | ALDH1A1GAATLR8KDM4EHRH4 | |
| SCHEMBL18023061 | 0.80 | TLR8 (0.49) | ALDH1A1GAATLR8KDM4EHRH4 | |
| SCHEMBL31574614 | 0.80 | L3MBTL1 (0.55) | ALDH1A1GAAKDM4EHRH4MAPT | |
| SCHEMBL28320053 | 0.79 | TLR8 (0.61) | ALDH1A1GAATLR8KDM4EHRH4 | |
| SCHEMBL18023034 | 0.79 | ALDH1A1 (0.60) | ALDH1A1GAATLR8KDM4EHRH4 | |
| SCHEMBL18641090 | 0.79 | ALDH1A1 (0.65) | ALDH1A1GAATLR8KDM4EHRH4 | |
| SCHEMBL9091724 | 0.79 | ALDH1A1 (0.60) | ALDH1A1GAATLR8KDM4EHRH4 | |
| SCHEMBL27389447 | 0.78 | ALDH1A1 (0.59) | ALDH1A1GAATLR8KDM4EHRH4 | |
| SCHEMBL27458779 | 0.77 | HRH4 (0.59) | ALDH1A1GAATLR8KDM4EHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2429568-B1 | MACROCYCLIC COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | ENANTA PHARM INC (US) | 2016-08-17 | — | — | EP | disclosed |