Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16419560 | 0.77 | CYP11B2 (0.50) | KMOCYP11B2CYP11B1 | |
| SCHEMBL3346194 | 0.77 | CYP11B1 (0.50) | CYP11B2CYP11B1 | |
| SCHEMBL27451301 | 0.76 | CHEK1 (0.59) | FYNCYP11B2CYP11B1 | |
| SCHEMBL9440147 | 0.74 | ALDH1A1 (0.56) | S1PR1KMODHFRKDM1AS1PR3 | |
| SCHEMBL25524170 | 0.73 | ALDH1A1 (0.53) | FYNCYP11B2CYP11B1 | |
| SCHEMBL12104619 | 0.73 | PFKFB3 (0.61) | PFKFB3 | |
| SCHEMBL17117158 | 0.72 | ALDH1A1 (0.54) | S1PR1KMODHFRKDM1AS1PR3 | |
| SCHEMBL23600958 | 0.72 | CYP19A1 (0.51) | FYNCYP11B2CYP11B1 | |
| SCHEMBL17463151 | 0.71 | CYP11B1 (0.51) | CYP11B2CYP11B1 | |
| SCHEMBL18850044 | 0.71 | CYP11B1 (0.50) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160235742-A1 | SPRAY DRY FORMULATIONS | GILEAD SCIENCES, INC. | 2016-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160235742-A1 | SPRAY DRY FORMULATIONS | FLT1, KDR, ERBB2 | FYN 32/4885S1PR1 240/4885KMO 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.