SCHEMBL18024032

SCHEMBL18024032

CN(CCO)CCN1CCN(C)CC1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 15/20 0.40
PAOX Q6QHF9 1/20 0.37
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27077590 0.91 ALDH1A1 (0.43) SIGMAR1TP53CYP1A2CYP2D6TSHR
SCHEMBL15065306 0.89 SIGMAR1 (0.46) SIGMAR1PAOXTP53CYP1A2CYP2D6
SCHEMBL18024083 0.88 SIGMAR1 (0.40) SIGMAR1PAOXTP53CYP1A2CYP2D6
SCHEMBL18024081 0.88 PAOX (0.43) SIGMAR1PAOXTSHR
SCHEMBL14385506 0.87 SIGMAR1 (0.47) SIGMAR1TP53CYP1A2CYP2D6TSHR
SCHEMBL17517722 0.87 SIGMAR1 (0.51) SIGMAR1TP53CYP1A2CYP2D6TSHR
SCHEMBL17528477 0.85 SIGMAR1 (0.50) SIGMAR1TP53CYP1A2CYP2D6TSHR
SCHEMBL791900 0.85 SIGMAR1 (0.50) SIGMAR1TP53CYP1A2CYP2D6TSHR
SCHEMBL13187897 0.83 PAOX (0.37) SIGMAR1PAOXTSHR
SCHEMBL2845937 0.83 PAOX (0.37) SIGMAR1PAOXTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361181-A1 DEGRADED AMINE SOLUTION AS PERFORMANCE ENHANCER HSUSTAINABILITY GMBH (DE) 2025-11-27 US claimed
EP-4565543-A1 DEGRADED AMINE SOLUTION AS PERFORMANCE ENHANCER Heidelberg Materials AG (DE) 2025-06-11 EP claimed
WO-2024028219-A1 DEGRADED AMINE SOLUTION AS PERFORMANCE ENHANCER HEIDELBERG MATERIALS AG (DE) 2024-02-08 WO claimed
EP-4317103-A1 DEGRADED AMINE SOLUTION AS PERFORMANCE ENHANCER Heidelberg Materials AG (DE) 2024-02-07 EP claimed
US-20250361181-A1 DEGRADED AMINE SOLUTION AS PERFORMANCE ENHANCER HSUSTAINABILITY GMBH (DE) 2025-11-27 US disclosed
EP-4565543-A1 DEGRADED AMINE SOLUTION AS PERFORMANCE ENHANCER Heidelberg Materials AG (DE) 2025-06-11 EP disclosed
WO-2024028219-A1 DEGRADED AMINE SOLUTION AS PERFORMANCE ENHANCER HEIDELBERG MATERIALS AG (DE) 2024-02-08 WO disclosed
EP-4317103-A1 DEGRADED AMINE SOLUTION AS PERFORMANCE ENHANCER Heidelberg Materials AG (DE) 2024-02-07 EP disclosed
WO-2016130968-A1 BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR YALE UNIVERSITY (US) 2016-08-18 WO disclosed