Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18024019 | 0.92 | ACE2 (0.52) | PAOXACE2KMT2ASIGMAR1KDM1A | |
| SCHEMBL18024000 | 0.92 | PAOX (0.43) | PAOXACE2TP53SMN1; SMN2KMT2A | |
| SCHEMBL4392341 | 0.89 | ACE2 (0.50) | PAOXACE2TP53SMN1; SMN2KMT2A | |
| SCHEMBL18024011 | 0.83 | SCN5A (0.46) | PAOXACE2SMN1; SMN2SIGMAR1KDM1A | |
| SCHEMBL4392290 | 0.83 | PAOX (0.48) | PAOXACE2USP2SIGMAR1KDM1A | |
| SCHEMBL8866 | 0.83 | PAOX (0.52) | PAOXKMT2AUSP2SIGMAR1KDM4E | |
| SCHEMBL8738045 | 0.82 | ACE2 (0.43) | PAOXACE2TP53SMN1; SMN2KMT2A | |
| SCHEMBL18024053 | 0.82 | HRH3 (0.50) | PAOXACE2SMN1; SMN2KDM1A | |
| SCHEMBL25387214 | 0.81 | PAOX (0.55) | PAOXUSP2SIGMAR1KDM4ECHRM2 | |
| SCHEMBL9368 | 0.81 | PAOX (0.55) | PAOXUSP2SIGMAR1KDM4ECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016130968-A1 | BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | YALE UNIVERSITY (US) | 2016-08-18 | — | — | WO | disclosed |