Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13822725 | 0.94 | ACE2 (0.48) | ACE2USP2PAOXGNAI3GNAO1 | |
| SCHEMBL4392341 | 0.91 | ACE2 (0.50) | ACE2USP2PAOXSIGMAR1KDM1A | |
| SCHEMBL21120466 | 0.88 | ALDH1A1 (0.50) | ACE2USP2PAOXGNAI3GNAO1 | |
| SCHEMBL13655836 | 0.88 | ACE2 (0.43) | ACE2USP2PAOXGNAI3GNAO1 | |
| SCHEMBL22416389 | 0.87 | ACE2 (0.52) | ACE2USP2PAOXGNAI3GNAO1 | |
| SCHEMBL10099919 | 0.85 | CYP2C19 (0.44) | ACE2USP2PAOXTLR8TLR7 | |
| SCHEMBL6739265 | 0.85 | CARM1 (0.46) | ACE2PAOXSIGMAR1KDM1AALDH1A1 | |
| SCHEMBL4392290 | 0.85 | PAOX (0.48) | ACE2USP2PAOXGNAI3GNAO1 | |
| SCHEMBL4396749 | 0.85 | ACE2 (0.48) | ACE2USP2PAOXGNAI3GNAO1 | |
| SCHEMBL4393776 | 0.85 | ACE2 (0.48) | ACE2USP2PAOXGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114188-A1 | IONIZABLE LIPIDS AND COMPOSITIONS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-06-22 | — | — | WO | disclosed |
| US-20220098210-A1 | QUINDOLINE COMPOUNDS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-03-31 | — | — | US | disclosed |
| US-8992991-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |
| US-8992991-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-05-24 | — | — | US | disclosed |
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220098210-A1 | QUINDOLINE COMPOUNDS AND USES THEREOF | RECQL, XPO7, XPOT | ACE2 3260/4885USP2 3840/4885PAOX 3315/4885 |
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | PEF1, FIBP, PARN | ACE2 4540/4885USP2 1621/4885PAOX 1525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.