SCHEMBL8866

SCHEMBL8866

CN1CCN(CCCO)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.52
SIGMAR1 Q99720 1/20 0.44
CHRM2 P08172 1/20 0.42
CHRM4 P08173 1/20 0.42
CHRM5 P08912 1/20 0.42
CHRM1 P11229 1/20 0.42
CHRM3 P20309 1/20 0.42
CSNK2A2 P19784 1/20 0.41
CSNK2B P67870 1/20 0.41
CSNK2A1 P68400 1/20 0.41
CSNK2A3 Q8NEV1 1/20 0.41
TSHR P16473 1/20 0.40
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
USP2 O75604 1/20 0.39
HPGD P15428 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPT P10636 1/20 0.38
KDM1A O60341 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9368 0.92 PAOX (0.55) PAOXSIGMAR1CHRM2CHRM4CHRM5
SCHEMBL25387214 0.92 PAOX (0.55) PAOXSIGMAR1CHRM2CHRM4CHRM5
SCHEMBL14258632 0.91 PAOX (0.46) PAOXSIGMAR1MAPT
SCHEMBL1619610 0.90 PAOX (0.59) PAOXSIGMAR1CHRM2CHRM4CHRM5
SCHEMBL1403872 0.90 PAOX (0.59) PAOXSIGMAR1CHRM2CHRM4CHRM5
SCHEMBL1404033 0.90 PAOX (0.59) PAOXSIGMAR1CHRM2CHRM4CHRM5
SCHEMBL1403846 0.90 PAOX (0.59) PAOXSIGMAR1CHRM2CHRM4CHRM5
SCHEMBL20231224 0.90 PAOX (0.59) PAOXSIGMAR1CHRM2CHRM4CHRM5
SCHEMBL1619627 0.90 PAOX (0.59) PAOXSIGMAR1CHRM2CHRM4CHRM5
SCHEMBL5880368 0.90 PAOX (0.59) PAOXSIGMAR1CHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4667511-A2 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY Tiba Biotech LLC (US) 2025-12-24 EP claimed
US-20240207187-A1 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY TIBA BIOTECH LLC (US) 2024-06-27 US claimed
CN-117915958-A Dendritic structures as non-viral vectors in gene delivery 蒂巴生物技术有限公司 2024-04-19 CN claimed
EP-4313170-A1 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY Tiba Biotech LLC (US) 2024-02-07 EP claimed
WO-2022212838-A1 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY TIBA BIOTECH LLC (US) 2022-10-06 WO claimed
CN-112612189-B Positive photoresist developing solution for panel display 福建省佑达环保材料有限公司 2022-06-14 CN claimed
CN-112612189-A Positive photoresist developing solution for panel display 福建省佑达环保材料有限公司 2021-04-06 CN claimed
CN-111905523-A Composition for removing sulfur dioxide from flue gas, preparation method thereof and flue gas desulfurization method 攀钢集团研究院有限公司 2020-11-10 CN claimed
CN-111905524-A Flue gas desulfurizing agent, preparation method thereof and flue gas desulfurizing method 攀钢集团研究院有限公司 2020-11-10 CN claimed
US-20200207779-A2 THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF Hongyun Biotech Co., Ltd. (CN) 2020-07-02 US claimed
WO-2000007980-A1 AMIDE DERIVATIVES WHICH ARE USEFUL AS CYTOKINE INHIBITORS ASTRAZENECA AB (SE) 2000-02-17 WO claimed
WO-1999059959-A1 BENZAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY CYTOKINES ASTRAZENECA AB (SE) 1999-11-25 WO claimed
EP-0790986-B1 ANILINE DERIVATIVES ZENECA LTD (GB) 1999-01-20 EP claimed
EP-0885198-A1 4-ANILINOQUINAZOLINE DERIVATIVES ZENECA LIMITED (GB) 1998-12-23 EP claimed
US-5821246-A USEFUL AS TYROSINE KINASE INHIBITORS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES SUCH AS CANCER ZENECA LIMITED (GB) 1998-10-13 US claimed
WO-1997032856-A1 4-ANILINOQUINAZOLINE DERIVATIVES ZENECA LIMITED (GB) 1997-09-12 WO claimed
EP-0790986-A1 ANILINE DERIVATIVES ZENECA LIMITED (GB) 1997-08-27 EP claimed
WO-1996015118-A1 ANILINE DERIVATIVES ZENECA LIMITED (GB) 1996-05-23 WO claimed
EP-0493846-B1 Multifunctional additive for lubricating oils MINI RICERCA SCIENT TECNOLOG (IT) 1994-02-23 EP claimed
EP-0493846-A1 Multifunctional additive for lubricating oils MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1992-07-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207187-A1 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY TLR3, TLR9, TLR6 PAOX 2038/4885SIGMAR1 511/4885CHRM2 4805/4885
US-20200207779-A2 THIENOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF ALK, MET, TIE1 PAOX 2160/4885SIGMAR1 4811/4885CHRM2 3668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.