Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14904691 | 0.94 | NPC1 (0.36) | NPC1RAB9ALMNAGRM1MAPK1 | |
| SCHEMBL15975671 | 0.90 | LMNA (0.33) | NPC1RAB9ALMNAGRM1MAPK1 | |
| SCHEMBL15975668 | 0.89 | NPC1 (0.35) | NPC1RAB9ALMNAMAPK1NAMPT | |
| SCHEMBL16269903 | 0.85 | NPC1 (0.36) | NPC1RAB9ALMNAGRM1MAPK1 | |
| SCHEMBL14904649 | 0.84 | LMNA (0.35) | NPC1RAB9ALMNAGRM1MAPK1 | |
| SCHEMBL15363512 | 0.84 | LMNA (0.35) | NPC1RAB9ALMNAGRM1MAPK1 | |
| SCHEMBL17590832 | 0.83 | NPC1 (0.35) | NPC1RAB9ALMNAGRM1MAPK1 | |
| SCHEMBL10278858 | 0.83 | NPC1 (0.37) | NPC1RAB9ALMNAGRM1MAPK1 | |
| SCHEMBL15910364 | 0.83 | GRM1 (0.38) | NPC1RAB9ALMNAGRM1MAPK1 | |
| SCHEMBL15975700 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422278-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2016-08-23 | — | — | US | disclosed |