SCHEMBL15975671

SCHEMBL15975671

[2H]C([2H])([2H])SCC(C)C(=O)N(C)c1cn(-c2cccnc2)nc1Cl

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
MAPK1 P28482 1/20 0.31
ALDH1A1 P00352 2/20 0.30
MAT2A P31153 1/20 0.30
FAAH O00519 1/20 0.30
KCNH2 Q12809 1/20 0.30
GRM1 Q13255 1/20 0.30
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14904649 0.94 LMNA (0.35) LMNANPC1RAB9AMAPK1ALDH1A1
SCHEMBL15975679 0.91 ALDH1A1 (0.32) LMNANPC1RAB9AMAPK1ALDH1A1
SCHEMBL18024985 0.90 NPC1 (0.34) LMNANPC1RAB9AMAPK1ALDH1A1
SCHEMBL4969070 0.89 LMNA (0.34) LMNANPC1RAB9AMAPK1ALDH1A1
SCHEMBL15975672 0.89 NPC1 (0.32) LMNANPC1RAB9AMAPK1ALDH1A1
SCHEMBL15346713 0.86 DGAT1 (0.35) LMNANPC1RAB9AMAPK1ALDH1A1
SCHEMBL18627098 0.86 LMNA (0.33) LMNANPC1RAB9AMAPK1ALDH1A1
SCHEMBL15975698 0.86 ALDH1A1 (0.32) LMNANPC1RAB9AMAPK1ALDH1A1
SCHEMBL15356824 0.86 LMNA (0.39) LMNANPC1RAB9AMAPK1ALDH1A1
SCHEMBL15975670 0.85 ALDH1A1 (0.34) LMNANPC1RAB9AMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9708288-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-07-18 US disclosed
US-9655365-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-05-23 US disclosed
US-9591857-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-03-14 US disclosed
US-9282739-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2016-03-15 US disclosed
US-8937083-B2 Pesticidal compositions and processes related thereto DowAgroSciences, LLC (US) 2015-01-20 US disclosed
US-8901153-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES, LLC. (US) 2014-12-02 US disclosed
US-8815271-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES, LLC. (US) 2014-08-26 US disclosed