Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | CASP3 | P42574 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15788093 | 0.80 | LCK (0.48) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL31378126 | 0.79 | TDP1 (0.66) | FOLH1TDP1CAPN1MEN1ABL1 | |
| SCHEMBL29869498 | 0.78 | FOLH1 (0.57) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL13881397 | 0.78 | OPRL1 (0.38) | — | |
| SCHEMBL12303008 | 0.78 | CNR1 (0.54) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL2259238 | 0.77 | FOLH1 (0.52) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL27233233 | 0.77 | TDP1 (0.69) | FOLH1TDP1CAPN1MEN1ABL1 | |
| SCHEMBL27233227 | 0.77 | TDP1 (0.69) | FOLH1TDP1CAPN1MEN1ABL1 | |
| SCHEMBL17931798 | 0.77 | FOLH1 (0.46) | FOLH1TDP1CASP3CASP1CASP2 | |
| SCHEMBL21110496 | 0.76 | TDP1 (0.51) | FOLH1TDP1CASP3CASP1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988492-B2 | Methods for post-fabrication functionalization of poly(ester ureas) | THE UNIVERSITY OF AKRON (US) | 2018-06-05 | — | — | US | disclosed |
| US-20160237212-A1 | METHODS FOR POST-FABRICATION FUNCTIONALIZATION OF POLY(ESTER UREAS) | THE UNIVERSITY OF AKRON (US) | 2016-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237212-A1 | METHODS FOR POST-FABRICATION FUNCTIONALIZATION OF POLY(ESTER UREAS) | PTMS, MUSK, DSTYK | FOLH1 3720/4885TDP1 1768/4885CASP3 833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.