Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | GLS | O94925 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1802799 | 1.00 | CYP4F2 (0.39) | CYP4F2CYP4A11GLSCYP2D6CYP2C9 | |
| SCHEMBL1803711 | 0.89 | CYP4F2 (0.40) | CYP4F2CYP4A11GLSCYP2D6CYP2C9 | |
| SCHEMBL1802570 | 0.89 | CYP4F2 (0.40) | CYP4F2CYP4A11GLSCYP2D6CYP2C9 | |
| SCHEMBL1799271 | 0.87 | SLC7A5 (0.34) | GLSCYP2D6CYP2C9CYP2C19RECQL | |
| SCHEMBL1799269 | 0.87 | SLC7A5 (0.34) | GLSCYP2D6CYP2C9CYP2C19RECQL | |
| SCHEMBL1802422 | 0.85 | CYP4F2 (0.38) | CYP4F2CYP4A11GLSCYP2D6CYP2C9 | |
| SCHEMBL1803069 | 0.85 | CYP4F2 (0.42) | CYP4F2CYP4A11GLSPTGESNR1H2 | |
| SCHEMBL1798529 | 0.85 | CYP4F2 (0.39) | CYP4F2CYP4A11GLSALDH1A1CA2 | |
| SCHEMBL1799283 | 0.80 | CYP4F2 (0.38) | CYP4F2CYP4A11CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1800114 | 0.77 | CYP4F2 (0.42) | CYP4F2CYP4A11GLSCYP2D6PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951954-B2 | Bezothiazol derivatives as Beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2011-05-31 | — | — | US | disclosed |
| US-20090062259-A1 | Bezothiazol Derivatives as Beta2 Adrenoreceptor Agonists | ASTRAZENECA AB (SE) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062259-A1 | Bezothiazol Derivatives as Beta2 Adrenoreceptor Agonists | ADRB2, ADRB1, ADRB3 | CYP4F2 1476/4885CYP4A11 459/4885GLS 4102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.