Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1802424 | 0.91 | HDAC1 (0.38) | BACE1CYP4F2CYP4A11HDAC1HDAC3 | |
| SCHEMBL1799273 | 0.88 | BACE1 (0.40) | BACE1HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL1800473 | 0.86 | GRIN2D (0.47) | BACE1CYP4F2CYP4A11HDAC1HDAC3 | |
| SCHEMBL1800151 | 0.85 | CYP4F2 (0.38) | BACE1CYP4F2CYP4A11HDAC1HDAC3 | |
| SCHEMBL4761208 | 0.85 | CYP4F2 (0.38) | BACE1CYP4F2CYP4A11HDAC1HDAC3 | |
| SCHEMBL1802573 | 0.85 | CYP4F2 (0.40) | BACE1CYP4F2CYP4A11HDAC1HDAC3 | |
| SCHEMBL1800114 | 0.85 | CYP4F2 (0.42) | BACE1CYP4F2CYP4A11HDAC1HDAC3 | |
| SCHEMBL4656457 | 0.82 | HDAC1 (0.42) | BACE1CYP4F2CYP4A11HDAC1HDAC3 | |
| SCHEMBL1799531 | 0.79 | CYP4F2 (0.43) | BACE1CYP4F2CYP4A11HDAC1HDAC3 | |
| SCHEMBL1802570 | 0.78 | CYP4F2 (0.40) | BACE1CYP4F2CYP4A11HDAC1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951954-B2 | Bezothiazol derivatives as Beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2011-05-31 | — | — | US | disclosed |
| US-20090062259-A1 | Bezothiazol Derivatives as Beta2 Adrenoreceptor Agonists | ASTRAZENECA AB (SE) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062259-A1 | Bezothiazol Derivatives as Beta2 Adrenoreceptor Agonists | ADRB2, ADRB1, ADRB3 | BACE1 377/4885CYP4F2 1476/4885CYP4A11 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.