Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEU4 | Q8WWR8 | 1/20 | 0.32 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.32 |
| ▸ | NEU2 | Q9Y3R4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13881437 | 0.84 | NEU4 (0.32) | NEU4NEU3NEU2 | |
| SCHEMBL18028045 | 0.82 | — | — | |
| SCHEMBL15706851 | 0.78 | FOLH1 (0.32) | — | |
| SCHEMBL14950991 | 0.78 | FOLH1 (0.32) | — | |
| SCHEMBL20960290 | 0.74 | — | — | |
| SCHEMBL21914884 | 0.73 | MAPT (0.50) | NEU4NEU3NEU2 | |
| SCHEMBL15028483 | 0.73 | — | — | |
| SCHEMBL23473527 | 0.73 | NOS3 (0.32) | — | |
| SCHEMBL17551030 | 0.72 | — | — | |
| SCHEMBL15197084 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148692-B1 | MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN | IPSEN PHARMA SAS (FR) | 2017-01-25 | — | — | EP | disclosed |
| US-20160244494-A1 | STABILIZED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244494-A1 | STABILIZED POLYPEPTIDES AND USES THEREOF | JAK2, STAT5A, STAT3 | NEU4 2672/4885NEU3 2518/4885NEU2 2918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.