⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27041682 | 0.83 | GGH (0.33) | — | |
| SCHEMBL27041677 | 0.83 | GGH (0.33) | — | |
| SCHEMBL23747679 | 0.82 | CTSL (0.31) | — | |
| SCHEMBL15028484 | 0.81 | BMP1 (0.30) | — | |
| SCHEMBL17906289 | 0.77 | CTSL (0.32) | — | |
| SCHEMBL14950991 | 0.75 | FOLH1 (0.32) | — | |
| SCHEMBL15706851 | 0.75 | FOLH1 (0.32) | — | |
| SCHEMBL15728239 | 0.74 | — | — | |
| SCHEMBL18028046 | 0.73 | NEU4 (0.32) | — | |
| SCHEMBL23589784 | 0.73 | CTSL (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4268901-A2 | IL-2R BETA-GAMMA C BINDING COMPOUNDS AND USES THEREOF | Medikine, Inc. (US) | 2023-11-01 | — | — | EP | disclosed |
| WO-2021158623-A1 | IL-7Rαγc BINDING COMPOUNDS | MEDIKINE, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
| WO-2012032181-A9 | ANTIBODY DERIVATIVES | ALLOZYNE, INC (US) | 2013-06-13 | — | — | WO | disclosed |