Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29082200 | 0.79 | KDM4E (0.50) | BCHEAHRKDM4EMAPTBACE1 | |
| SCHEMBL27757985 | 0.71 | BCHE (0.45) | BCHEAHRKDM4EMAPTBACE1 | |
| SCHEMBL6315677 | 0.71 | AHR (0.47) | BCHEAHRBACE1KEAP1NR3C1 | |
| SCHEMBL29851874 | 0.71 | MAPT (0.56) | KDM4EMAPTKMT2AELANE | |
| SCHEMBL8680185 | 0.71 | MAPT (0.56) | KDM4EMAPTKMT2AELANE | |
| SCHEMBL593512 | 0.71 | AHR (0.50) | BCHEAHRBACE1KEAP1NR3C1 | |
| SCHEMBL6089123 | 0.70 | NR3C1 (0.51) | BCHEAHRKDM4EMAPTKMT2A | |
| Methane SCHEMBL27929614 | 0.69 | AHR (0.48) | BCHEAHRBACE1KEAP1NR3C1 | |
| SCHEMBL517207 | 0.68 | SIGMAR1 (0.54) | KDM4EMAPTKMT2AELANE | |
| SCHEMBL29657743 | 0.68 | SIGMAR1 (0.54) | KDM4EMAPTKMT2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016134145-A9 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-02-16 | — | — | WO | disclosed |
| WO-2016134145-A2 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-08-25 | — | — | WO | disclosed |