Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18029160 | 0.87 | GRIA1 (0.42) | MAPTALDH1A1RECQLSLC7A5ALPI | |
| SCHEMBL19871274 | 0.86 | MAPT (0.40) | MAPTALDH1A1RECQLSLC7A5ALPI | |
| SCHEMBL18029093 | 0.86 | PLA2G2A (0.44) | MAPTALDH1A1RECQLSLC7A5ALPI | |
| SCHEMBL18029300 | 0.85 | AKR1B1 (0.40) | MAPTALDH1A1RECQLSLC7A5ALPI | |
| SCHEMBL18029088 | 0.85 | ALDH1A1 (0.39) | MAPTALDH1A1RECQLSLC7A5ALPI | |
| SCHEMBL18029362 | 0.82 | MAPT (0.38) | MAPTALDH1A1RECQLSLC7A5ALPI | |
| SCHEMBL18029326 | 0.82 | MAPT (0.38) | MAPTALDH1A1RECQLSLC7A5ALPI | |
| SCHEMBL18029282 | 0.82 | PLA2G2A (0.47) | MAPTALDH1A1RECQLSLC7A5GRIK1 | |
| SCHEMBL18028963 | 0.82 | PTGDR2 (0.40) | MAPTALDH1A1RECQLSLC7A5ALPI | |
| SCHEMBL19871279 | 0.81 | MAPT (0.37) | MAPTALDH1A1RECQLSLC7A5ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240229090-A1 | MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-07-11 | — | — | US | disclosed |
| US-20230287466-A1 | MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH (US) | 2023-09-14 | — | — | US | disclosed |
| US-20180044291-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2018-02-15 | — | — | US | disclosed |
| WO-2016134145-A2 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2016-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044291-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | CYP4F2, POR, CYP4F3 | MAPT 4241/4885ALDH1A1 449/4885RECQL 1048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.