Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Xylene SCHEMBL8660591 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1705904 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL5068661 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL31313 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL11432043 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL34 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL29991938 | 0.97 | GAA (0.62) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1594407 | 0.95 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| Water SCHEMBL214962 | 0.95 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1345322 | 0.95 | GAA (0.59) | GAALMNAALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551221-B1 | Process for the preparation of star or network multiblock polycondensates by coupling di- or multi-adhehydes, and polycondensate thus obtained | ATOCHEM ELF SA (FR) | 1997-06-04 | — | — | EP | claimed |
| US-5395884-A | Process for manufacturing multisequence star or network polycondensates by di- or multi-aldehyde coupling, and polycondensates obtained | ELF ATOCHEM S.A. (FR) | 1995-03-07 | — | — | US | claimed |
| US-5346956-A | Process for manufacturing multisequence star or network polycondensates by di- or multi-aldehyde coupling, and polycondensates obtained | ELF ATOCHEM S.A. (FR) | 1994-09-13 | — | — | US | claimed |
| WO-2022031913-A1 | VISCOELASTIC-SURFACTANT TREATMENT FLUIDS HAVING OXIDIZER | SAUDI ARABIAN OIL COMPANY (SA) | 2022-02-10 | — | — | WO | disclosed |
| CN-106432038-B | A kind of method and its special-purpose catalyst synthesizing N-phenylmaleimide | 中国石油化工股份有限公司 | 2019-11-08 | — | — | CN | disclosed |
| CN-106432038-A | Method for synthesizing N-phenylmaleimide and special catalyst for method | 中国石油化工股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| US-9520569-B2 | Aryl compounds for application in a highly polar solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-13 | — | — | US | disclosed |
| US-9306169-B2 | Electronic device, polymer compound, organic compound, and method of producing polymer compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-04-05 | — | — | US | disclosed |
| US-20140231717-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |
| EP-2693508-A1 | ELECTRONIC DEVICE, POLYMER COMPOUND, ORGANIC COMPOUND, AND METHOD OF PRODUCING POLYMER COMPOUND | Sumitomo Chemical Company Limited (JP) | 2014-02-05 | — | — | EP | disclosed |
| US-20140024785-A1 | ELECTRONIC DEVICE, POLYMER COMPOUND, ORGANIC COMPOUND, AND METHOD OF PRODUCING POLYMER COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-01-23 | — | — | US | disclosed |
| WO-1997002253-A1 | BENZYLHYDROXYLAMINES AND INTERMEDIATES USED TO PREPARE THEM | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-23 | — | — | WO | disclosed |
| US-5591816-A | POLY(N-CYCLOHEXYLMALEIMIDE) | ATOCHEM (FR) | 1997-01-07 | — | — | US | disclosed |
| US-5561207-A | USING COORDINATION CATALYST | ELF ATOCHEM S.A. (FR) | 1996-10-01 | — | — | US | disclosed |
| US-5395884-A | Process for manufacturing multisequence star or network polycondensates by di- or multi-aldehyde coupling, and polycondensates obtained | ELF ATOCHEM S.A. (FR) | 1995-03-07 | — | — | US | disclosed |
| US-5391628-A | A block terpolymers consisting of an acrylic or/and methacrylic monomer terminated with a hydroxy functional end group | ELF ATOCHEM S.A. (FR) | 1995-02-21 | — | — | US | disclosed |
| US-5346956-A | Process for manufacturing multisequence star or network polycondensates by di- or multi-aldehyde coupling, and polycondensates obtained | ELF ATOCHEM S.A. (FR) | 1994-09-13 | — | — | US | disclosed |
| US-5294674-A | High molecular weight polymers and ionomers | ATOCHEM (FR) | 1994-03-15 | — | — | US | disclosed |
| US-5264527-A | Block copolymerization using vinylaromatics, methacrylates or acyclics | ELF ATOCHEM S.A. (FR) | 1993-11-23 | — | — | US | disclosed |
| US-4681944-A | Process for preparing certain 1-lower alkanoyl or benzoyl-4-(lower alkanoyl or benzoyl-methylidene)-1,4-dihydropyridines or acid addition salts thereof | BRITISH NUCLEAR GROUP SELLAFIELD LIMITED (GB) | 1987-07-21 | — | — | US | disclosed |