SCHEMBL1803282

SCHEMBL1803282

O=S(=O)(O)c1ccc(CCCO)c(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.49
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
ALOX15 P16050 1/20 0.39
CYP2C19 P33261 1/20 0.39
TBXA2R P21731 1/20 0.39
EPAS1 Q99814 1/20 0.38
ALDH1A1 P00352 2/20 0.36
MAPT P10636 1/20 0.36
CASP6 P55212 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
DHFR P00374 1/20 0.36
MCL1 Q07820 1/20 0.35
LMNA P02545 1/20 0.34
NAAA Q02083 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1805327 0.95 CA2 (0.44) CA2CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL1805325 0.90 CYP2C19 (0.41) CA2CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL1803280 0.87 CYP1A2 (0.39) CA2CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL1802451 0.85 CA2 (0.68) CA2
SCHEMBL1805324 0.85 CYP1A2 (0.39) CA2CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL1805323 0.83 CYP2C19 (0.41) CA2CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL2252252 0.83 S1PR3 (0.46) CA2CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL2251107 0.83 S1PR3 (0.46) CA2CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL2246809 0.83 S1PR3 (0.46) CA2CYP1A2CYP3A4CYP2D6ALOX15
SCHEMBL2247782 0.83 S1PR3 (0.46) CA2CYP1A2CYP3A4CYP2D6ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 CA2 1279/4885CYP1A2 487/4885CYP3A4 1680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.