SCHEMBL18035807

SCHEMBL18035807

C=CC(CCCC)[n+]1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.35
ADRA2A P08913 2/20 0.35
ADORA3 P0DMS8 2/20 0.35
CHRM1 P11229 2/20 0.35
ACHE P22303 2/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 2/20 0.35
SLC6A3 Q01959 2/20 0.35
ABCB11 O95342 1/20 0.35
ESR1 P03372 1/20 0.35
PGR P06401 1/20 0.35
HTR1A P08908 1/20 0.35
DRD1 P21728 1/20 0.35
TBXA2R P21731 1/20 0.35
PTGS1 P23219 1/20 0.35
PDE4A P27815 1/20 0.35
ADRA1A P35348 1/20 0.35
OPRM1 P35372 1/20 0.35
DRD3 P35462 1/20 0.35
KCNH2 Q12809 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3479352 0.98 KMT2A (0.37) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL6557911 0.94 CHRM2 (0.38) CHRM2ADRA2AADORA3CHRM1ACHE
Bromide SCHEMBL1548089 0.91 RAD52 (0.43) CHRM2ADRA2AADORA3CHRM1ACHE
Acetic Acid SCHEMBL15210170 0.89 CA2 (0.34) ACHETSHRMAPK1
Iodide SCHEMBL11381556 0.86
Bromide SCHEMBL9299877 0.86 HSP90AA1 (0.31) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL16650419 0.79
Iodide SCHEMBL11395813 0.78
SCHEMBL11126349 0.74 CHRM2 (0.33) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL13762473 0.73 CHRM2 (0.41) CHRM2ADRA2AADORA3CHRM1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2638123-B1 WORKING MEDIUM FOR ABSORPTION HEAT PUMPS EVONIK DEGUSSA GMBH (DE) 2016-08-31 EP claimed