Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.43 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.43 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.43 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.43 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557911 | 0.96 | CHRM2 (0.38) | RAD52HSP90AA1CHRM2ADRA2AADORA3 | |
| SCHEMBL18035807 | 0.91 | CHRM2 (0.35) | RAD52HSP90AA1CHRM2ADRA2AADORA3 | |
| Hydrochloric Acid SCHEMBL3479352 | 0.89 | KMT2A (0.37) | RAD52HSP90AA1CHRM2ADRA2AADORA3 | |
| Bromide SCHEMBL9299877 | 0.85 | HSP90AA1 (0.31) | RAD52HSP90AA1CHRM2ADRA2AADORA3 | |
| Iodide SCHEMBL11381556 | 0.82 | — | — | |
| Acetic Acid SCHEMBL15210170 | 0.81 | CA2 (0.34) | ACHETSHRMAPK1 | |
| SCHEMBL16650419 | 0.75 | — | — | |
| Bromide SCHEMBL28419938 | 0.74 | RAD52 (0.48) | RAD52HSP90AA1CHRM2ADRA2AADORA3 | |
| Bromide SCHEMBL28845552 | 0.74 | RAD52 (0.48) | RAD52HSP90AA1CHRM2ADRA2AADORA3 | |
| Bromide SCHEMBL28057294 | 0.74 | RAD52 (0.48) | RAD52HSP90AA1CHRM2ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4144416-A1 | FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER | Johnson & Johnson Consumer Inc. (US) | 2023-03-08 | — | — | EP | disclosed |
| EP-3349723-B1 | SUNSCREEN COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS | JOHNSON & JOHNSON CONSUMER INC (US) | 2022-03-16 | — | — | EP | disclosed |
| EP-3349863-B1 | FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER | JOHNSON & JOHNSON CONSUMER INC (US) | 2022-01-19 | — | — | EP | disclosed |
| US-11173106-B2 | Compositions comprising a superhydrophilic amphiphilic copolymer and a micellar thickener | JOHNSON & JOHNSON CONSUMER INC. (US) | 2021-11-16 | — | — | US | disclosed |
| EP-3349723-A1 | SUNSCREEN COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS | Johnson & Johnson Consumer Inc. (US) | 2018-07-25 | — | — | EP | disclosed |
| EP-3349863-A1 | FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER | Johnson & Johnson Consumer Inc. (US) | 2018-07-25 | — | — | EP | disclosed |
| EP-2486063-B1 | SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND PROCESSES FOR MAKING THE SAME | AKZO NOBEL CHEMICALS INT BV (NL) | 2018-03-28 | — | — | EP | disclosed |
| EP-2024476-B1 | COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF | JOHNSON & JOHNSON CONSUMER INC (US) | 2017-11-15 | — | — | EP | disclosed |
| EP-2021448-B1 | COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF | JOHNSON & JOHNSON CONSUMER INC (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-2021447-B1 | COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF | JOHNSON & JOHNSON CONSUMER INC (US) | 2017-09-13 | — | — | EP | disclosed |
| EP-2021447-A1 | COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2009-02-11 | — | — | EP | disclosed |
| US-7446087-B2 | Compositions comprising low-DP polymerized surfactants and methods of use thereof | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2008-11-04 | — | — | US | disclosed |
| US-7446088-B2 | Compositions comprising low-DP polymerized surfactants and methods of use thereof | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2008-11-04 | — | — | US | disclosed |
| US-7417020-B2 | low-irritation; for treating the skin, hair, or vaginal region | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2008-08-26 | — | — | US | disclosed |
| WO-2007130237-A2 | COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF | JOHNSON & JOHNSON CONSUMER, COMPANIES, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007130236-A2 | COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007130238-A1 | COMPOSITIONS COMPRISING LOW-DP POLYMERIZED SURFACTANTS AND METHODS OF USE THEREOF | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
| US-20070259797-A1 | Compositions comprising low-DP polymerized surfactants and methods of use thereof | JOHNSON & JOHNSON CONSUMER INC. | 2007-11-08 | — | — | US | disclosed |
| US-20070259798-A1 | Compositions comprising low-DP polymerized surfactants and methods of use thereof | JOHNSON & JOHNSON CONSUMER INC. | 2007-11-08 | — | — | US | disclosed |
| US-20070259796-A1 | Compositions comprising low-DP polymerized surfactants and methods of use thereof | JOHNSON & JOHNSON CONSUMER INC. | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259796-A1 | Compositions comprising low-DP polymerized surfactants and methods of use thereof | DSG1, DSP, CUTA | CHRM2 3471/4885CHRM1 3645/4885ACHE 968/4885 |
| US-20070259797-A1 | Compositions comprising low-DP polymerized surfactants and methods of use thereof | DSG1, DSP, CUTA | CHRM2 3471/4885CHRM1 3645/4885ACHE 968/4885 |
| US-20070259798-A1 | Compositions comprising low-DP polymerized surfactants and methods of use thereof | DSG1, DSP, CUTA | CHRM2 3471/4885CHRM1 3645/4885ACHE 968/4885 |
| US-11173106-B2 | Compositions comprising a superhydrophilic amphiphilic copolymer and a micellar thickener | ABHD16A, DSG1, CUTA | CHRM2 2479/4885CHRM1 2675/4885ACHE 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.