Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | RGS12 | O14924 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292131 | 0.81 | USP2 (0.45) | USP2KDM4EPKML3MBTL1ALOX15 | |
| SCHEMBL287393 | 0.80 | SLC7A5 (0.50) | USP2KDM4EPKML3MBTL1ALOX15 | |
| SCHEMBL287394 | 0.80 | SLC7A5 (0.50) | USP2KDM4EPKML3MBTL1ALOX15 | |
| SCHEMBL5875624 | 0.80 | SLC7A5 (0.50) | USP2KDM4EPKML3MBTL1ALOX15 | |
| SCHEMBL9291690 | 0.80 | THRB (0.44) | USP2KDM4EPKML3MBTL1ALOX15 | |
| SCHEMBL9291686 | 0.80 | THRB (0.44) | USP2KDM4EPKML3MBTL1ALOX15 | |
| SCHEMBL5288482 | 0.79 | USP2 (0.50) | USP2KDM4EPKML3MBTL1ALOX15 | |
| SCHEMBL15345630 | 0.79 | USP2 (0.50) | USP2KDM4EPKML3MBTL1ALOX15 | |
| SCHEMBL29351668 | 0.79 | USP2 (0.50) | USP2KDM4EPKML3MBTL1ALOX15 | |
| SCHEMBL668470 | 0.79 | USP2 (0.50) | USP2KDM4EPKML3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3061753-A1 | ENANTIO-SELECTIVE SYNTHESIS OF NON-NATURAL AMINO ACIDS | Universita' Degli Studi "G. d'Annunzio" Chieti-Pescara (IT) | 2016-08-31 | — | — | EP | disclosed |