Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 5/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.47 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5875640 | 0.84 | GRIA1 (0.53) | GRIA1GRIA3GRIA4GRIA2MAPT | |
| SCHEMBL11030460 | 0.84 | GRIA1 (0.53) | GRIA1GRIA3GRIA4GRIA2MAPT | |
| SCHEMBL6046222 | 0.84 | GRIA1 (0.53) | GRIA1GRIA3GRIA4GRIA2MAPT | |
| SCHEMBL18035912 | 0.83 | SLC7A5 (0.48) | GRIA1GRIA3GRIA4GRIA2MAPT | |
| SCHEMBL287393 | 0.81 | SLC7A5 (0.50) | GRIA1GRIA3GRIA4GRIA2MAPT | |
| SCHEMBL5323478 | 0.81 | SLC7A5 (0.58) | GRIA1GRIA3GRIA4GRIA2MAPT | |
| SCHEMBL5875624 | 0.81 | SLC7A5 (0.50) | GRIA1GRIA3GRIA4GRIA2MAPT | |
| SCHEMBL16585559 | 0.81 | SLC7A5 (0.58) | GRIA1GRIA3GRIA4GRIA2MAPT | |
| SCHEMBL287394 | 0.81 | SLC7A5 (0.50) | GRIA1GRIA3GRIA4GRIA2MAPT | |
| SCHEMBL296690 | 0.79 | SLC7A5 (0.50) | MAPTMEN1CYP2C9KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3061753-A1 | ENANTIO-SELECTIVE SYNTHESIS OF NON-NATURAL AMINO ACIDS | Universita' Degli Studi "G. d'Annunzio" Chieti-Pescara (IT) | 2016-08-31 | — | — | EP | disclosed |