Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | TK1 | P04183 | 2/20 | 0.48 |
| ▸ | PNP | P00491 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbovir SCHEMBL19237554 | 1.00 | NR1I2 (0.56) | NR1I2ALBPDE4DADORA3HPRT1 | |
| Carbovir SCHEMBL8447674 | 1.00 | NR1I2 (0.56) | NR1I2ALBPDE4DADORA3HPRT1 | |
| Carbovir SCHEMBL9867194 | 1.00 | NR1I2 (0.56) | NR1I2ALBPDE4DADORA3HPRT1 | |
| Carbovir SCHEMBL3778804 | 1.00 | NR1I2 (0.56) | NR1I2ALBPDE4DADORA3HPRT1 | |
| Carbovir SCHEMBL30552224 | 0.91 | ADORA3 (0.51) | NR1I2ALBPDE4DADORA3HPRT1 | |
| SCHEMBL14015633 | 0.88 | BCHE (0.52) | NR1I2ALBPDE4DADORA3HPRT1 | |
| SCHEMBL9685090 | 0.88 | BCHE (0.52) | NR1I2ALBPDE4DADORA3HPRT1 | |
| SCHEMBL9704154 | 0.86 | BCHE (0.57) | ADORA3HPRT1BCHEPNPBLM | |
| SCHEMBL23587713 | 0.86 | NR1I2 (0.56) | NR1I2ALBPDE4DADORA3HPRT1 | |
| SCHEMBL6554844 | 0.86 | NR1I2 (0.56) | NR1I2ALBPDE4DADORA3HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2009 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502166-A | Method of treating HIV with cabozivir and rilpivirine | VIIV保健公司 | 2022-05-13 | — | — | CN | claimed |
| US-20190330635-A1 | ANTIVIRAL AGENT AND METHOD FOR TREATING VIRAL INFECTION | HUANG, LI-MIN (TW) | 2019-10-31 | — | — | US | claimed |
| CN-110214013-A | Antivirotic and the method for treating virus infection | 黄立民 | 2019-09-06 | — | — | CN | claimed |
| EP-2846788-A1 | USE OF COMPOUNDS FOR THE TREATMENT OF PAIN | Akron Molecules AG (AT) | 2015-03-18 | — | — | EP | claimed |
| EP-2308885-B1 | Novel compounds and methods for therapy | GILEAD SCIENCES INC (US) | 2014-11-19 | — | — | EP | claimed |
| EP-2245037-B1 | NOVEL COMPOUNDS AND METHODS FOR THERAPY | GILEAD SCIENCES INC (US) | 2014-06-18 | — | — | EP | claimed |
| WO-2013167743-A1 | USE OF COMPOUNDS FOR THE TREATMENT OF PAIN | AKRON MOLECULES GMBH (AT) | 2013-11-14 | — | — | WO | claimed |
| US-8415095-B2 | Use of nucleoside derivatives comprising a citrate group for the production of antibodies having an affinity for triphosphorylated nucleosides | Centre National de la Recherche-Scientifique-CNRS (FR) | 2013-04-09 | — | — | US | claimed |
| US-8268352-B2 | Modified release composition for highly soluble drugs | TORRENT PHARMACEUTICALS LIMITED (IN) | 2012-09-18 | — | — | US | claimed |
| US-8263125-B2 | Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients | TORRENT PHARMACEUTICALS LIMITED (IN) | 2012-09-11 | — | — | US | claimed |
| CN-1083073-A | New lipophilic oligopeptides with immunoregulatory activity | IAF BIOCHEM INT (CA) | 1994-03-02 | — | — | CN | claimed |
| US-5281616-A | Treatment of human immunodeficiency virus infections | GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) | 1994-01-25 | — | — | US | claimed |
| WO-1993020100-A1 | NOVEL LIPOPHILIC OLIGOPEPTIDES WITH IMMUNOMODULATING ACTIVITY | BIOCHEM PHARMA INC. (CA) | 1993-10-14 | — | — | WO | claimed |
| WO-1993017035-A1 | 2'ISODIDEOXY-β-D-NUCLEOSIDES AS STABLE ANTIVIRAL AGENTS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1993-09-02 | — | — | WO | claimed |
| US-5192788-A | PORPHYRIN ANTIVIRAL COMPOSITIONS | GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) | 1993-03-09 | — | — | US | claimed |
| WO-1992013868-A1 | PHOSPHATIDIC ACIDS AND THEIR PREPARATION | GENZYME LIMITED (GB) | 1992-08-20 | — | — | WO | claimed |
| US-5109016-A | Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions | GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) | 1992-04-28 | — | — | US | claimed |
| EP-0393499-A1 | Process for preparing carbovir and new intermediate products therefor | F. HOFFMANN-LA ROCHE AG (CH) | 1990-10-24 | — | — | EP | claimed |
| EP-0361831-A1 | Antiviral nucleoside combination | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-04-04 | — | — | EP | claimed |
| WO-1989011277-A2 | PORPHYRIN AND PHTHALOCYANINE ANTIVIRAL COMPOSITIONS | GEORGIA STATE UNIVERSITY FOUNDATION, INC. (US) | 1989-11-30 | — | — | WO | claimed |