SCHEMBL9685090

SCHEMBL9685090

[CH2]CC1C=CC(n2cnc3c(=O)[nH]c(N)nc32)C1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.52
ADORA3 P0DMS8 1/20 0.47
PNP P00491 3/20 0.47
HPRT1 P00492 6/20 0.46
ADCY5 O95622 2/20 0.44
NR1I2 O75469 1/20 0.43
ALB P02768 1/20 0.43
PDE4D Q08499 1/20 0.43
TK1 P04183 1/20 0.43
XDH P47989 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9704154 0.89 BCHE (0.57) BCHEADORA3PNPHPRT1
SCHEMBL14015633 0.88 BCHE (0.52) BCHEADORA3PNPHPRT1ADCY5
Carbovir SCHEMBL8447674 0.88 NR1I2 (0.56) BCHEADORA3PNPHPRT1ADCY5
Carbovir SCHEMBL3778804 0.88 NR1I2 (0.56) BCHEADORA3PNPHPRT1ADCY5
Carbovir SCHEMBL19237554 0.88 NR1I2 (0.56) BCHEADORA3PNPHPRT1ADCY5
Carbovir SCHEMBL9867194 0.88 NR1I2 (0.56) BCHEADORA3PNPHPRT1ADCY5
Carbovir SCHEMBL180360 0.88 NR1I2 (0.56) BCHEADORA3PNPHPRT1ADCY5
Carbovir SCHEMBL30552224 0.86 ADORA3 (0.51) BCHEADORA3PNPHPRT1ADCY5
SCHEMBL15046016 0.85 BCHE (0.58) BCHEADORA3HPRT1XDH
SCHEMBL9704169 0.85 BCHE (0.58) BCHEADORA3HPRT1XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0468866-A1 Novel carbocyclic analogs of certain nucleosides MERRELL DOW PHARMACEUTICALS INC. (US) 1992-01-29 EP disclosed
EP-0468119-A1 Novel carbocyclic analogs of certain nucleosides MERRELL DOW PHARMACEUTICALS INC. (US) 1992-01-29 EP disclosed