SCHEMBL18036722

SCHEMBL18036722

C=C(CC=Cc1ccccc1)C(=O)OC[Si](C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 1/20 0.49
MAOB P27338 5/20 0.42
MAOA P21397 3/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
LMNA P02545 1/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
MMP12 P39900 1/20 0.36
GLA P06280 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
THRB P10828 1/20 0.36
TSHR P16473 1/20 0.36
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
RAB9A P51151 1/20 0.35
ADORA3 P0DMS8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1792779 0.84 MEN1 (0.55) PAMMAOBMAOAMEN1KMT2A
SCHEMBL96726 0.81 PAM (0.56) PAMMAOBMAOAMEN1KMT2A
SCHEMBL5608312 0.81 PAM (0.59) PAMMAOBMAOALMNAMMP1
SCHEMBL3382895 0.80 LMNA (0.55) PAMMAOBKMT2ALMNATDP1
SCHEMBL409074 0.80 PAM (0.51) PAMMAOBMAOAMEN1KMT2A
SCHEMBL2490104 0.80 PAM (0.51) PAMMAOBMAOAMEN1KMT2A
SCHEMBL455010 0.80 KDM4E (0.51) PAMMAOBMEN1KMT2ATDP1
SCHEMBL5246224 0.80 PAM (0.47) PAMMAOBMAOAMEN1KMT2A
SCHEMBL27901586 0.79 PAM (0.58) PAMMAOBMAOALMNAMMP1
SCHEMBL3803971 0.78 PAM (0.46) PAMMAOBMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351727-B2 Copolymer formulation for directed self-assembly, methods of manufacture thereof and articles comprising the same DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-16 US claimed
US-9765214-B2 Copolymer formulation for directed self-assembly, methods of manufacture thereof and articles comprising the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-09-19 US claimed
US-20160251508-A1 COPOLYMER FORMULATION FOR DIRECTED SELF-ASSEMBLY, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-09-01 US claimed
US-20160251539-A1 COPOLYMER FORMULATION FOR DIRECTED SELF-ASSEMBLY, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-09-01 US claimed
US-10351727-B2 Copolymer formulation for directed self-assembly, methods of manufacture thereof and articles comprising the same DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-16 US disclosed
US-9840637-B2 Copolymer formulation for directed self-assembly, methods of manufacture thereof and articles comprising the same DOW GLOBAL TECHNOLOGIES LLC (US) 2017-12-12 US disclosed
US-9772554-B2 Copolymer formulation for directed self-assembly, methods of manufacture thereof and articles comprising the same DOW GLOBAL TECHNOLOGIES LLC (US) 2017-09-26 US disclosed
US-9765214-B2 Copolymer formulation for directed self-assembly, methods of manufacture thereof and articles comprising the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-09-19 US disclosed
US-20160251508-A1 COPOLYMER FORMULATION FOR DIRECTED SELF-ASSEMBLY, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-09-01 US disclosed
US-20160251538-A1 COPOLYMER FORMULATION FOR DIRECTED SELF-ASSEMBLY, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-09-01 US disclosed
US-20160254141-A1 COPOLYMER FORMULATION FOR DIRECTED SELF-ASSEMBLY, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-09-01 US disclosed
US-20160251539-A1 COPOLYMER FORMULATION FOR DIRECTED SELF-ASSEMBLY, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-09-01 US disclosed