Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.87 |
| ▸ | CHAT | P28329 | 2/20 | 0.83 |
| ▸ | EP300 | Q09472 | 3/20 | 0.82 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.82 |
| ▸ | AURKA | O14965 | 2/20 | 0.82 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.82 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4287977 | 0.98 | NAA50 (0.87) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL28290381 | 0.97 | NAA50 (0.89) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL3242015 | 0.97 | NAA50 (0.89) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL27877871 | 0.95 | NAA50 (0.89) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL27571436 | 0.95 | NAA50 (0.89) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL25252 | 0.95 | NAA50 (0.89) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL26116845 | 0.95 | NAA50 (0.89) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL502465 | 0.95 | NAA50 (0.89) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL4368641 | 0.95 | NAA50 (0.89) | NAA50CHATEP300KAT5AURKA | |
| SCHEMBL59721 | 0.95 | NAA50 (0.88) | NAA50CHATEP300KAT5AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851393-B2 | KAS-III free FA synthesis | WILLIAM MARSH RICE UNIVERSITY (US) | 2020-12-01 | — | — | US | disclosed |
| US-20180148746-A1 | KAS-III FREE FA SYNTHESIS | WILLIAM MARSH RICE UNIVERSITY | 2018-05-31 | — | — | US | disclosed |
| WO-2016137897-A1 | KASIII-FREE FA SYNTHESIS | WILLIAM MARSH RICE UNIVERSITY (US) | 2016-09-01 | — | — | WO | disclosed |