SCHEMBL59721

SCHEMBL59721

CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CCN

nearest known ligand 0.89

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NAA50 Q9GZZ1 2/20 0.88
▸ CHAT P28329 2/20 0.84
▸ EP300 Q09472 3/20 0.83
▸ KAT5 Q92993 2/20 0.83
▸ AURKA O14965 2/20 0.83
▸ KAT2B Q92831 1/20 0.83
▸ CREBBP Q92793 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19857088 1.00 NAA50 (0.88) NAA50CHATEP300KAT5AURKA
Ammonia Solution, Strong SCHEMBL60556 0.99 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
SCHEMBL22556110 0.97 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
SCHEMBL29530678 0.97 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
SCHEMBL59962 0.97 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
SCHEMBL16585519 0.97 NAA50 (0.84) NAA50CHATEP300KAT5AURKA
SCHEMBL15299842 0.97 NAA50 (0.86) NAA50CHATEP300KAT5AURKA
SCHEMBL19693052 0.97 NAA50 (0.86) NAA50CHATEP300KAT5AURKA
SCHEMBL284786 0.96 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL18918369 0.96 NAA50 (0.85) NAA50CHATEP300KAT5AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4305173-A1 RECOMBINANT MICROORGANISMS AND USES THEREFOR Lanzatech, Inc. (US) 2024-01-17 — — EP claimed
CN-116615549-A Recombinant microorganism and use thereof 朗泽科技有限公司 2023-08-18 — — CN claimed
WO-2022192865-A9 RECOMBINANT MICROORGANISMS AND USES THEREFOR LANZATECH, INC. (US) 2023-02-09 — — WO claimed
EP-3406724-B1 RECOMBINANT MUTANT MICROORGANISMS HAVING ACRYLIC ACID PRODUCTIVITY AND METHOD FOR PRODUCING ACRYLIC ACID USING SAME HANWHA CHEMICAL CORP (KR) 2022-12-14 — — EP claimed
CN-108884465-B Modified microorganism having acrylic acid-producing ability and method for producing acrylic acid using the same 韩华石油化学株式会社 2022-11-15 — — CN claimed
WO-2022192865-A1 RECOMBINANT MICROORGANISMS AND USES THEREFOR LANZATECH, INC. (US) 2022-09-15 — — WO claimed
US-20220282289-A1 RECOMBINANT MICROORGANISMS AND USES THEREFOR UNITED STATES DEPARTMENT OF ENERGY 2022-09-08 — — US claimed
US-10450593-B2 Type II fatty acid synthesis enzymes in reverse β-oxidation WILLIAM MARSH RICE UNIVERSITY (US) 2019-10-22 — — US claimed
US-9994881-B2 Functionalized carboxylic acids and alcohols by reverse fatty acid oxidation in engineered microbes WILLIAM MARSH RICE UNIVERSITY (US) 2018-06-12 — — US claimed
EP-3099763-A1 TYPE II FATTY ACID SYSTHESIS ENZYMES IN REVERSE B-OXIDATION William Marsh Rice University (US) 2016-12-07 — — EP claimed
WO-2009089457-A1 METHODS FOR PRODUCING 3-HYDROXYPROPIONIC ACID AND COMPOUNDS THEREOF NOVOZYMES A/S (DK) 2009-07-16 — — WO claimed
EP-1575881-B1 ALANINE 2,3- AMINOMUTASE NOVOZYMES AS (DK) 2009-05-27 — — EP claimed
US-20080124785-A1 ALANINE 2, 3-AMINOMUTASE CARGILL, INCORPORATED 2008-05-29 — — US claimed
US-7309597-B2 To convert alpha-alanine to beta-alanine, beta-alanine, pantothenic acid, 3-hydroxypropionic acid CARGILL, INCORPORATED (US) 2007-12-18 — — US claimed
WO-2007047680-A2 INCREASING THE ACTIVITY OF RADICAL S-ADENOSYL METHIONINE (SAM) ENZYMES CARGILL, INCORPORATED (US) 2007-04-26 — — WO claimed
EP-1575881-A4 ALANINE 2,3- AMINOMUTASE CARGILL INC (US) 2006-02-01 — — EP claimed
US-20050221466-A1 Alanine 2,3,aminomutase CARGILL, INCORPORATED 2005-10-06 — — US claimed
EP-1575881-A2 ALANINE 2,3- AMINOMUTASE Cargill, Incorporated (US) 2005-09-21 — — EP claimed
EP-1575881-A3 ALANINE 2,3- AMINOMUTASE Cargill, Incorporated (US) 2005-08-04 — — EP claimed
WO-2003062173-A2 ALANINE 2,3- AMINOMUTASE CARGILL, INCORPORATED (US) 2003-07-31 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080124785-A1 ALANINE 2, 3-AMINOMUTASE ALAD, AGXT, ABAT NAA50 664/4885CHAT 1228/4885EP300 3306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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