Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902933 | 0.84 | HTR2A (0.41) | LMNAALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL8849136 | 0.81 | PPOX (0.41) | LMNAALDH1A1L3MBTL1KDM4EATM | |
| SCHEMBL15995459 | 0.80 | LMNA (0.38) | LMNAALDH1A1L3MBTL1KDM4EHTT | |
| SCHEMBL21335513 | 0.78 | LMNA (0.51) | LMNAALDH1A1L3MBTL1KDM4EHTT | |
| SCHEMBL29082966 | 0.76 | LMNA (0.37) | LMNAALDH1A1L3MBTL1ATMHTT | |
| SCHEMBL19088275 | 0.76 | PPOX (0.42) | LMNAALDH1A1L3MBTL1KDM4EATM | |
| SCHEMBL1905388 | 0.74 | ERCC1 (0.35) | ALDH1A1HTTERN1TSHR | |
| SCHEMBL17423613 | 0.74 | MAPK1 (0.43) | LMNAALDH1A1L3MBTL1KDM4EMAPT | |
| SCHEMBL30902343 | 0.74 | CYP1A2 (0.52) | LMNAALDH1A1L3MBTL1KDM4EATM | |
| SCHEMBL17423632 | 0.74 | TSHR (0.45) | LMNAALDH1A1L3MBTL1ATMTACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158891-A1 | SALTS AND SOLID FORMS AND PROCESSES OF PREPARING A PI3K INHIBITOR | INCYTE CORPORATION (US) | 2021-08-12 | — | — | WO | disclosed |
| EP-3262046-A1 | SALTS OF PI3K INHIBITOR AND PROCESSES FOR THEIR PREPARATION | Incyte Corporation (US) | 2018-01-03 | — | — | EP | disclosed |
| WO-2016138363-A1 | SALTS OF PI3K INHIBITOR AND PROCESSES FOR THEIR PREPARATION | INCYTE CORPORATION (US) | 2016-09-01 | — | — | WO | disclosed |