Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | OGG1 | O15527 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4434733 | 0.83 | SMN1; SMN2 (0.40) | RAB9ANPC1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL28652779 | 0.80 | CYP2D6 (0.40) | RAB9ANPC1SMN1; SMN2RECQLCYP2C9 | |
| SCHEMBL18530405 | 0.77 | CYP2D6 (0.38) | RAB9ANPC1SMN1; SMN2RECQLCYP2C9 | |
| SCHEMBL18530402 | 0.77 | CYP2D6 (0.38) | RAB9ANPC1SMN1; SMN2RECQLCYP2C9 | |
| SCHEMBL18039462 | 0.76 | OGG1 (0.39) | RAB9ANPC1SMN1; SMN2RECQLCYP2C9 | |
| SCHEMBL4477529 | 0.75 | KCNN4 (0.34) | CES2CES1 | |
| SCHEMBL27808403 | 0.73 | OGG1 (0.37) | RAB9ANPC1SMN1; SMN2RECQLCYP2C9 | |
| SCHEMBL27647920 | 0.71 | POLB (0.49) | RAB9ANPC1SMN1; SMN2RECQLCYP2C9 | |
| SCHEMBL27890515 | 0.70 | MEN1 (0.42) | RAB9ANPC1SMN1; SMN2RECQLCYP2C9 | |
| SCHEMBL4334002 | 0.70 | HTT (0.38) | RAB9ANPC1SMN1; SMN2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016135751-A1 | NOVEL PROCESS FOR THE PREPARATION OF SACUBITRIL AND ITS INTERMEDIATES | MYLAN LABORATORIES LIMITED (IN) | 2016-09-01 | — | — | WO | disclosed |