Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27745565 | 0.86 | KMT2A (0.42) | MEN1KMT2AGAACYP3A4CYP2D6 | |
| SCHEMBL27647920 | 0.84 | POLB (0.49) | MEN1KMT2ASMN1; SMN2NPC1RECQL | |
| 4-Chloroaniline SCHEMBL27831633 | 0.84 | MAOA (0.44) | MEN1KMT2ANPC1GAACYP3A4 | |
| SCHEMBL28299259 | 0.83 | ALOX5 (0.46) | MEN1KMT2ASMN1; SMN2NPC1RECQL | |
| Chlorobenzene SCHEMBL27484099 | 0.81 | KMT2A (0.42) | MEN1KMT2AGAACYP3A4CYP2D6 | |
| SCHEMBL28807393 | 0.81 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL27805296 | 0.79 | LMNA (0.43) | KMT2ASMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL28652779 | 0.74 | CYP2D6 (0.40) | MEN1KMT2ASMN1; SMN2NPC1RECQL | |
| SCHEMBL28902273 | 0.73 | DGAT1 (0.42) | SMN1; SMN2LMNAALDH1A1PMP22 | |
| SCHEMBL30234788 | 0.73 | DGAT1 (0.42) | SMN1; SMN2LMNAALDH1A1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712636-A | Compounds and compositions as TLR activity modulators | IRM LLC | 2012-10-03 | — | — | CN | disclosed |