SCHEMBL1804003

SCHEMBL1804003

NS(=O)(=O)c1cc2c(s1)S(=O)(=O)CCC2O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CA2 P00918 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10795922 1.00 CA2 (1.00) CA2
SCHEMBL10513374 1.00 CA2 (1.00) CA2
SCHEMBL10513839 0.92 CA2 (0.84) CA2
SCHEMBL9740319 0.84 CA2 (1.00) CA2
SCHEMBL10514253 0.84 CA2 (0.74) CA2
SCHEMBL1123037 0.84 CA2 (1.00) CA2
SCHEMBL9740316 0.84 CA2 (1.00) CA2
Hydrochloric Acid SCHEMBL10512111 0.82 CA2 (1.00) CA2
SCHEMBL10512797 0.82 CA2 (0.69) CA2
SCHEMBL9525429 0.79 CA2 (0.65) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730697-B2 Ocular drug delivery devices BAUSCH HEALTH AMERICAS, INC. (US) 2023-08-22 US claimed
US-20190133934-A1 Ocular Drug Delivery Devices ATON PHARMA, INC. (BM) 2019-05-09 US claimed
EP-2493459-B1 OCULAR DRUG DELIVERY DEVICES ATON PHARMA INC (US) 2016-08-24 EP claimed
US-20140187497-A1 Ocular Drug Delivery Devices LOUISIANA STATE UNIVERSITY AGRICULTURAL AND MECHANICAL COLLEGE (US) 2014-07-03 US claimed
EP-2493459-A1 OCULAR DRUG DELIVERY DEVICES Aton Pharma, Inc. (US) 2012-09-05 EP claimed
US-20120213840-A1 OCULAR STRIPS VALEANT INTERNATIONAL (BARBADOS) SRL 2012-08-23 US claimed
US-20120215184-A1 CYLINDRICAL OCULAR INSERTS VALEANT INTERNATIONAL (BARBADOS) SRL 2012-08-23 US claimed
WO-2012112636-A1 CYLINDRICAL OCULAR INSERTS VALEANT INTERNATIONAL (BARBADOS) SRL (BB) 2012-08-23 WO claimed
WO-2012112638-A1 CROSS REFERENCE TO RELATED APPLICATIONS VALEANT INTERNATIONAL (BARBADOS) SRL (BB) 2012-08-23 WO claimed
US-20110129516-A1 OCULAR DRUG DELIVERY DEVICES ATON PHARMA, INC. 2011-06-02 US claimed
WO-2011053841-A1 OCULAR DRUG DELIVERY DEVICES ATON PHARMA, INC. (US) 2011-05-05 WO claimed
EP-0189690-B1 SUBSTITUTED AROMATIC SULFONAMIDES, THEIR PREPARATION AND OPHTHALMIC COMPOSITIONS CONTAINING THEM MERCK & CO. INC. (US) 1989-03-01 EP claimed
US-4677115-A Antiglaucoma thieno-thiopyran and thieno-thiepin sulfonamide derivatives, compositions, and method of use thereof MERCK & CO., INC. (US) 1987-06-30 US claimed
EP-0189690-A1 Substituted aromatic sulfonamides, their preparation and ophthalmic compositions containing them MERCK & CO. INC. (US) 1986-08-06 EP claimed
CN-118403165-A Application of Nrf2/SLC7A11/GPX4 shaft in preparation of sleep deprivation medicine 河北大学 2024-07-30 CN disclosed
CN-114557992-B Application of compound pharmaceutical composition in preparation of medicine for treating interstitial pneumonia 中国药科大学 2024-02-27 CN disclosed
US-11730697-B2 Ocular drug delivery devices BAUSCH HEALTH AMERICAS, INC. (US) 2023-08-22 US disclosed
US-4730013-A POLYVINYL ALCOHOL, GLYCERIN, HYDROXYPROPYL METHYL CELLULOSE PHTHALATE MERCK & CO., INC. (US) 1988-03-08 US disclosed
US-4677115-A Antiglaucoma thieno-thiopyran and thieno-thiepin sulfonamide derivatives, compositions, and method of use thereof MERCK & CO., INC. (US) 1987-06-30 US disclosed
EP-0189690-A1 Substituted aromatic sulfonamides, their preparation and ophthalmic compositions containing them MERCK & CO. INC. (US) 1986-08-06 EP disclosed