Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | WDR5 | P61964 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19949474 | 0.83 | KMT2A (0.57) | CYP2C9WDR5KMT2AALDH1A1DDAH1 | |
| SCHEMBL18040453 | 0.83 | CYP2C9 (0.39) | CYP2C9WDR5KMT2AALDH1A1DDAH1 | |
| SCHEMBL28064578 | 0.82 | KMT2A (0.56) | CYP2C9WDR5KMT2AALDH1A1DDAH1 | |
| SCHEMBL12440025 | 0.76 | CYP2C9 (0.42) | CYP2C9WDR5KMT2AALDH1A1DDAH1 | |
| SCHEMBL14237996 | 0.75 | CYP2C9 (0.48) | CYP2C9WDR5KMT2AALDH1A1DDAH1 | |
| SCHEMBL14141752 | 0.74 | CYP2C9 (0.43) | CYP2C9WDR5KMT2AALDH1A1DDAH1 | |
| SCHEMBL14142363 | 0.73 | CYP2C9 (0.41) | CYP2C9WDR5KMT2AALDH1A1DDAH1 | |
| SCHEMBL27990433 | 0.70 | ALDH1A1 (0.45) | CYP2C9WDR5KMT2AALDH1A1DDAH1 | |
| SCHEMBL29186335 | 0.69 | NPC1 (0.42) | CYP2C9WDR5KMT2AALDH1A1DDAH1 | |
| SCHEMBL14988972 | 0.67 | MAPT (0.57) | CYP2C9WDR5KMT2AALDH1A1DDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2532665-B1 | BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | XUANZHU PHARMA CO LTD (CN) | 2016-09-07 | — | — | EP | claimed |