Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.42 |
| ▸ | RAB9A | P51151 | 9/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | WDR5 | P61964 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ENGASE | Q8NFI3 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | FASN | P49327 | 2/20 | 0.41 |
| ▸ | SARM1 | Q6SZW1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19949474 | 0.87 | KMT2A (0.57) | NPC1RAB9ASMN1; SMN2CYP2C9LMNA | |
| SCHEMBL28064578 | 0.86 | KMT2A (0.56) | NPC1RAB9ASMN1; SMN2CYP2C9LMNA | |
| SCHEMBL14988972 | 0.84 | MAPT (0.57) | NPC1RAB9ASMN1; SMN2CYP2C9LMNA | |
| SCHEMBL27990433 | 0.79 | ALDH1A1 (0.45) | NPC1RAB9ACYP2C9LMNAMAPT | |
| SCHEMBL27677793 | 0.74 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2CYP2C9LMNA | |
| SCHEMBL27990381 | 0.70 | RUNX1 (0.52) | CYP2C9LMNAMAPTALDH1A1DDAH1 | |
| SCHEMBL18040452 | 0.69 | CYP2C9 (0.41) | NPC1RAB9ASMN1; SMN2CYP2C9LMNA | |
| SCHEMBL13547174 | 0.69 | CYP2C9 (0.62) | NPC1RAB9ACYP2C9LMNAMAPT | |
| SCHEMBL23988420 | 0.68 | CYP2C9 (0.51) | NPC1RAB9ASMN1; SMN2CYP2C9LMNA | |
| SCHEMBL23957939 | 0.68 | CYP2C9 (0.45) | NPC1RAB9ASMN1; SMN2CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117534657-A | Synthetic method and application of rabeprazole analogue | 湖北省医药工业研究院有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-117534657-A | Synthetic method and application of rabeprazole analogue | 湖北省医药工业研究院有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-117534657-A | Synthetic method and application of rabeprazole analogue | 湖北省医药工业研究院有限公司 | 2024-02-09 | — | — | CN | disclosed |