SCHEMBL1804210

SCHEMBL1804210

NCc1cc(Cl)ccc1S(=O)(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.39
DDR1 Q08345 2/20 0.38
CYP3A4 P08684 2/20 0.38
MAPT P10636 2/20 0.38
HIF1A Q16665 2/20 0.38
PNMT P11086 1/20 0.38
MEN1 O00255 1/20 0.38
SLC22A1 O15245 1/20 0.38
USP2 O75604 1/20 0.38
LMNA P02545 1/20 0.38
HSP90AA1 P07900 1/20 0.38
HSPD1 P10809 1/20 0.38
HSPA5 P11021 1/20 0.38
IDO1 P14902 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
CASP1 P29466 1/20 0.38
HTT P42858 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1807106 0.85 CYP2A6 (0.39) CYP2A6CYP3A4MAPTPNMTLMNA
SCHEMBL14991863 0.85 CYP3A4 (0.50) DDR1CYP3A4MAPTHIF1AMEN1
SCHEMBL7549791 0.83 DDR1 (0.46) DDR1CYP3A4MAPTHIF1AMEN1
SCHEMBL1808822 0.83 MAPT (0.44) DDR1CYP3A4MAPTHIF1AMEN1
SCHEMBL1808821 0.83 HIF1A (0.39) DDR1CYP3A4MAPTHIF1AMEN1
Hydrochloric Acid SCHEMBL1016268 0.81 CA1 (0.41) CYP2A6CYP3A4MAPTHIF1AMEN1
SCHEMBL4486953 0.81 ADRA1D (0.48) CYP2A6DDR1CYP3A4MEN1KMT2A
SCHEMBL1804206 0.81 GRIK1 (0.40) DDR1CYP3A4MAPTHIF1AMEN1
SCHEMBL12997839 0.80 DDR1 (0.54) DDR1
Hydrochloric Acid SCHEMBL1262739 0.80 ADRA1D (0.47) CYP2A6DDR1CYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118662642-A Gamma-aminobutyric acid receptor antagonist composition and application thereof in preparation of medicines for treating gastric cancer 威海市立医院 2024-09-20 CN disclosed
CN-117045803-A Gamma-aminobutyric acid receptor antagonist composition and application thereof in preparation of medicines for treating gastric cancer 威海市立医院 2023-11-14 CN disclosed
US-8404036-B2 Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-03-26 US disclosed
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123784-A1 WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME IK, RB1, COL1A1 CYP2A6 2793/4885DDR1 1191/4885CYP3A4 1680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.