Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18499050 | 0.81 | RARB (0.40) | ALDH1A1KMT2APTK2BKDM4EHPGD | |
| SCHEMBL18151941 | 0.81 | RARB (0.40) | ALDH1A1KMT2APTK2BKDM4EHPGD | |
| SCHEMBL18044460 | 0.81 | RARB (0.40) | ALDH1A1KMT2APTK2BKDM4EHPGD | |
| SCHEMBL2929463 | 0.77 | HTT (0.40) | ALDH1A1KMT2AKDM4EHPGDLMNA | |
| SCHEMBL18044471 | 0.75 | MAPT (0.44) | ALDH1A1KMT2AKDM4EHPGDLMNA | |
| SCHEMBL18499051 | 0.75 | MAPT (0.44) | ALDH1A1KMT2AKDM4EHPGDLMNA | |
| SCHEMBL18151911 | 0.75 | MAPT (0.44) | ALDH1A1KMT2AKDM4EHPGDLMNA | |
| SCHEMBL2476042 | 0.74 | ALDH1A1 (0.42) | ALDH1A1KMT2APTK2BKDM4EHPGD | |
| SCHEMBL18151908 | 0.71 | RARB (0.46) | ALDH1A1KMT2APTK2BHPGDLMNA | |
| SCHEMBL25788066 | 0.71 | ALDH1A1 (0.84) | ALDH1A1KMT2APTK2BKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067351-A1 | COMPOUND HAVING HIGHER INHIBITION OF PROTEIN KINASE G ACTIVITY AND PREPARATION METHOD THEREFOR | Jenkem Technology Co. Ltd. (Tianjin) (CN) | 2016-09-14 | — | — | EP | disclosed |