Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18299092 | 0.90 | GAA (0.46) | ALDH1A1MAPTTSHRGAASMN1; SMN2 | |
| SCHEMBL26977968 | 0.87 | HPGD (0.42) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL29099043 | 0.87 | HPGD (0.42) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL29099046 | 0.87 | HPGD (0.42) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL15227428 | 0.87 | HPGD (0.42) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL26978292 | 0.87 | HPGD (0.42) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5151599 | 0.87 | HPGD (0.42) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL26978667 | 0.87 | HPGD (0.42) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9473363 | 0.86 | THRB (0.40) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL9473367 | 0.86 | THRB (0.40) | ALDH1A1MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10100030-B2 | Carboxymethyl piperidine derivative | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2018-10-16 | — | — | US | disclosed |
| EP-3067349-B1 | CARBOXYMETHYL PIPERIDINE DERIVATIVE | KISSEI PHARMACEUTICAL (JP) | 2018-02-28 | — | — | EP | disclosed |
| US-20160289206-A1 | CARBOXYMETHYL PIPERIDINE DERIVATIVE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2016-10-06 | — | — | US | disclosed |
| EP-3067349-A1 | CARBOXYMETHYL PIPERIDINE DERIVATIVE | Kissei Pharmaceutical Co., Ltd. (JP) | 2016-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10100030-B2 | Carboxymethyl piperidine derivative | TACR1, CYP3A5, CNR1 | HPGD 612/4885ALDH1A1 165/4885MEN1 3434/4885 |
| US-20160289206-A1 | CARBOXYMETHYL PIPERIDINE DERIVATIVE | TACR1, CYP3A5, CNR1 | HPGD 612/4885ALDH1A1 165/4885MEN1 3434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.