Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151599 | 1.00 | HPGD (0.42) | HPGDRECQLDPP4ALDH1A1MEN1 | |
| SCHEMBL15227428 | 1.00 | HPGD (0.42) | HPGDRECQLDPP4ALDH1A1MEN1 | |
| SCHEMBL26978292 | 1.00 | HPGD (0.42) | HPGDRECQLDPP4ALDH1A1MEN1 | |
| SCHEMBL26978667 | 1.00 | HPGD (0.42) | HPGDRECQLDPP4ALDH1A1MEN1 | |
| SCHEMBL29099046 | 1.00 | HPGD (0.42) | HPGDRECQLDPP4ALDH1A1MEN1 | |
| SCHEMBL26977968 | 1.00 | HPGD (0.42) | HPGDRECQLDPP4ALDH1A1MEN1 | |
| SCHEMBL13711178 | 0.90 | GAA (0.45) | ALDH1A1MAPTTSHRGAA | |
| SCHEMBL26125021 | 0.87 | HPGD (0.44) | HPGDRECQLDPP4ALDH1A1MEN1 | |
| SCHEMBL18044508 | 0.87 | HPGD (0.41) | HPGDRECQLALDH1A1MEN1KMT2A | |
| SCHEMBL14501404 | 0.86 | L3MBTL1 (0.40) | ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116997555-A | Novel thienopyrimidinone derivatives | 豪夫迈·罗氏有限公司 | 2023-11-03 | — | — | CN | disclosed |