⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496533 | 1.00 | — | — | |
| SCHEMBL4818781 | 1.00 | — | — | |
| SCHEMBL15516489 | 0.89 | TSHR (0.31) | — | |
| SCHEMBL15508046 | 0.89 | TSHR (0.31) | — | |
| SCHEMBL5536884 | 0.81 | — | — | |
| SCHEMBL5633650 | 0.80 | APLNR (0.33) | — | |
| SCHEMBL9304034 | 0.80 | APLNR (0.33) | — | |
| SCHEMBL2160578 | 0.80 | APLNR (0.33) | — | |
| SCHEMBL14271077 | 0.79 | HPGD (0.32) | — | |
| SCHEMBL16928564 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265229-B2 | Method for synthesizing macrosphelides | LEAD CHEMICAL CO., LTD. (JP) | 2007-09-04 | — | — | US | claimed |
| US-20060030720-A1 | Method for synthesizing macrosphelides | LEAD CHEMICAL CO., LTD. (JP) | 2006-02-09 | — | — | US | claimed |
| EP-2571353-B1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBVIE INC (US) | 2017-08-09 | — | — | EP | disclosed |
| US-20140322165-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL DISCOVERY INC (US) | 2014-10-30 | — | — | US | disclosed |
| US-8846951-B2 | Modulators of 5-HT receptors and methods of use thereof | ABBVIE INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-8771665-B2 | Inhibitors of hepatitis C virus polymerase | COCRYSTAL DISCOVERY, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-20120183496-A1 | INHIBITORS OF HEPATITIS C VIRUS POLYMERASE | COCRYSTAL DISCOVERY, INC. (US) | 2012-07-19 | — | — | US | disclosed |
| US-20110118231-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2011-05-19 | — | — | US | disclosed |
| US-7365174-B2 | Azalide and azalactam derivatives and method for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2008-04-29 | — | — | US | disclosed |
| US-7265229-B2 | Method for synthesizing macrosphelides | LEAD CHEMICAL CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |
| US-7265229-B2 | Method for synthesizing macrosphelides | LEAD CHEMICAL CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |
| US-20070042974-A1 | Nozel azalide and azalactam derivatives and method for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1661904-A1 | NOVEL AZALIDE AND AZALACTAM DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2006-05-31 | — | — | EP | disclosed |
| US-20060030720-A1 | Method for synthesizing macrosphelides | LEAD CHEMICAL CO., LTD. (JP) | 2006-02-09 | — | — | US | disclosed |
| US-20060030720-A1 | Method for synthesizing macrosphelides | LEAD CHEMICAL CO., LTD. (JP) | 2006-02-09 | — | — | US | disclosed |
| WO-2004048360-A1 | METHOD OF SYNTHESIZING MACROSPHELIDES | LEAD CHEMICAL CO., LTD. (JP) | 2004-06-10 | — | — | WO | disclosed |