Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633650 | 1.00 | APLNR (0.33) | APLNR | |
| SCHEMBL2160578 | 1.00 | APLNR (0.33) | APLNR | |
| SCHEMBL9794756 | 0.84 | — | — | |
| SCHEMBL13619240 | 0.83 | — | — | |
| SCHEMBL16940575 | 0.81 | TRPA1 (0.31) | — | |
| SCHEMBL14380063 | 0.80 | — | — | |
| SCHEMBL4818781 | 0.80 | — | — | |
| SCHEMBL1804486 | 0.80 | — | — | |
| SCHEMBL6496533 | 0.80 | — | — | |
| SCHEMBL12432576 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265229-B2 | Method for synthesizing macrosphelides | LEAD CHEMICAL CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |
| US-7265229-B2 | Method for synthesizing macrosphelides | LEAD CHEMICAL CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |
| US-5332807-A | Process of producing 8A- and 9A-azalide antibiotics | MERCK & CO., INC. (US) | 1994-07-26 | — | — | US | disclosed |
| WO-1994015617-A1 | 8A-AZA AND 9A-AZA MACROLIDE ANTIBIOTICS, AND A PROCESS FOR PRODUCING SAME AND METHODS OF USE | MERCK & CO., INC. (US) | 1994-07-21 | — | — | WO | disclosed |