Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 1.00 |
| ▸ | CA2 | P00918 | 5/20 | 1.00 |
| ▸ | F2 | P00734 | 3/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.61 |
| ▸ | ACLY | P53396 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070438 | 1.00 | CA1 (1.00) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL11038427 | 0.83 | CA1 (0.71) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL9808163 | 0.83 | CA1 (0.70) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL29385668 | 0.83 | CA1 (0.70) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL6906930 | 0.82 | CA1 (0.69) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL184213 | 0.81 | CA1 (0.68) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL29364988 | 0.81 | CA1 (0.68) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL397094 | 0.81 | CA1 (0.68) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL22022107 | 0.80 | CA1 (0.67) | CA1CA2ACLY | |
| SCHEMBL1648602 | 0.79 | CA1 (0.66) | CA1CA2F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4572734-A | 3,5-DICHLORO-2-HYDROXY-BENZENESULFONAMIDE; DESICCANT AND DEFOLIANT FOR COTTON | BAYER AKTIENGESELLSCHAFT (DE) | 1986-02-25 | — | — | US | claimed |
| US-4556733-A | Process for the preparation of 2-hydroxybenzenesulfonamide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-12-03 | — | — | US | claimed |
| CN-118271212-A | Caryophyllane derivative, preparation method, application and pharmaceutical composition | 赣江中药创新中心 | 2024-07-02 | — | — | CN | disclosed |
| US-8404036-B2 | Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20110123784-A1 | WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2011-05-26 | — | — | US | disclosed |
| EP-1476449-A1 | FUSED BICYCLIC-N-BRIDGED-HETEROAROMATIC CARBOXAMIDES FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-17 | — | — | EP | disclosed |
| US-6774212-B2 | FOR THERAPY OF VIRAL INFECTION OR AS AN ASSAY STANDARD OR REAGENT | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-08-10 | — | — | US | disclosed |
| WO-2003070732-A1 | FUSED BICYCLIC-N-BRIDGED-HETEROAROMATIC CARBOXAMIDES FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN COMPANY (US) | 2003-08-28 | — | — | WO | disclosed |
| EP-1252178-A1 | ALPHA-KETOAMIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | Bristol-Myers Squibb Pharma Company (US) | 2002-10-30 | — | — | EP | disclosed |
| US-20020123468-A1 | Alpha-ketoamide inhibitors of hepatitis C virus NS3 protease | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-09-05 | — | — | US | disclosed |
| WO-2001040262-A1 | ALPHA-KETOAMIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-06-07 | — | — | WO | disclosed |
| US-4572734-A | 3,5-DICHLORO-2-HYDROXY-BENZENESULFONAMIDE; DESICCANT AND DEFOLIANT FOR COTTON | BAYER AKTIENGESELLSCHAFT (DE) | 1986-02-25 | — | — | US | disclosed |
| US-4572734-A | 3,5-DICHLORO-2-HYDROXY-BENZENESULFONAMIDE; DESICCANT AND DEFOLIANT FOR COTTON | BAYER AKTIENGESELLSCHAFT (DE) | 1986-02-25 | — | — | US | disclosed |
| US-4556733-A | Process for the preparation of 2-hydroxybenzenesulfonamide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-12-03 | — | — | US | disclosed |
| US-4425153-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS & CO. (US) | 1984-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110123784-A1 | WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME | IK, RB1, COL1A1 | CA1 798/4885CA2 1279/4885F2 703/4885 |
| US-20020123468-A1 | Alpha-ketoamide inhibitors of hepatitis C virus NS3 protease | CES1, CYP51A1, SPINT2 | CA1 695/4885CA2 869/4885F2 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.